Impact of bariatric surgery on non-alcoholic fatty liver disease

• Authors: Piotr Major , Michał Pędziwiatr , Mateusz Rubinkiewicz , Maciej Stanek , Anna Głuszewska , Magdalena Pisarska , Piotr Małczak , Andrzej Budzyński , Piotr Budzyński

Abstracts

EN

Introduction; p to 300 million people have the body mass index (BMI) greater than 30 kg/m2. Obesity is the cause of many serious diseases, such as type 2 diabetes, hypertension, and non-alcoholic fatty liver disease (NAFLD). Bariatric surgery is the only effective method of achieving weight loss in patients with morbid obesity. Objectives: The aim of the study was to assess the impact of bariatric surgery on non-alcoholic fatty liver disease in patients operated on due to morbid obesity. Material and Methods: We included 20 patients who were qualified for bariatric procedures based on BMI > 40 kg/ m2 or BMI > 35kg/m2 with the presence of comorbidities. The average body weight in the group was 143.85kg, with an average BMI of 49.16kg/m2. Before the procedure, we evaluated the severity of non-alcoholic fatty liver disease in each patient using the Sheriff-Saadeh ultrasound scale. We also evaluated the levels of liver enzymes. Follow-up evaluation was performed twelve months after surgery. Results: Twelve months after surgery, the average weight was 102.34 kg. The mean %WL was 33.01%, %EWL was 58.8%, and %EBMIL was 61.37%. All patients showed remission of fatty liver disease. Liver damage, evaluated with ultrasound imaging, decreased from an average of 1.85 on the Sheriff-Saadeh scale, before surgery, to 0.15 twelve months after surgery (p < 0.001). As regards liver enzymes, the level of alanine aminotransferase decreased from 64.5 (U/l) to 27.95 (U/l) (p < 0.001), and the level of aspartate aminotransferase decreased from 54.4 (U/l) to 27.2 (U/l). Conclusions: Bariatric procedures not only lead to a significant and lasting weight loss, but they also contribute to the reduction of fatty liver disease and improve liver function.

Keywords

EN

non-alcoholic fatty liver disease; bariatric surgery; morbid obesity

• Publisher: Index Copernicus International
• Journal: Polish Journal of Surgery
• Year: 2017
• Volume: 89(2)
• Pages: 1-4

Contributors

author

Piotr Major

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Michał Pędziwiatr

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Mateusz Rubinkiewicz

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Maciej Stanek

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Anna Głuszewska

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Magdalena Pisarska

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Piotr Małczak

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Andrzej Budzyński

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Piotr Budzyński

Identifiers

DOI

10.5604/01.3001.0009.6003