Accelerated postoperative radiotherapy in patients with advanced larynx cancer

• Authors: Jadwiga Kubrak , Maria Chosia , Piotr Maj , Alina Jarema

Abstracts

EN

Aim: The aim of study was test effi cacy of accelerated postoperative radiotherapy – concomitant boost in patients with advanced larynx cancer. Methods and Materials: The prospective study included 112 patients with advanced larynx cancer after radical surgical treatment. Patients had postoperative radiation therapy, conventional (C) or accelerated (CB). Results: The 3-year overall survival in CB was 59%, in C – 58% (p=0,2), 3-year locoregional control in CB – 83%, in C – 75% (p=0.01), the 3-year disease free survival was in CB – 72%, C – 66% (p=0.1). Conclusion: Concomitant boost postoperative radition therapy did not improove overall survival, loco-regional control, disease free survival. Patients with close surgical margins, longer interval between surgery and radiation, high level of hemoglobin, T4 had benefi t from accelerated radiotherapy.

Keywords

EN

larynx cancer; overall treatment time; postoperative accelerated radiotherapy

• Journal: Otolaryngologia Polska
• Year: 2010
• Volume: 64(7)
• Pages: 60-64

Dates

published

2018-04-27

Contributors

author

Jadwiga Kubrak

author

Maria Chosia

author

Piotr Maj

author

Alina Jarema