The authors present a case of 64 years old woman treated with palliative radiotherapy due to maxillary sinus cancer – non-operative stage. The cancer-relative pain couldn’t be released after radiotherapy and with pain killers. She used NSAIDs and opioid drugs. Before chemiotherapy she was undertaken intranasal sinus operation as a palliative operation. Maxillary sinus was opened. The pain after operation diminished signifi cantly. She died 2 and a half months later, during chemiotherapy, but free of pain.