Recommendation for use of Sinupret extract in acute rhinosinusitis
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Acute and chronic rhinosinusitis is the most common problem encountered in ENT practice. Nearly all cases of acute rhinosinusitis are of viral background. Further course of the disease is determined by the condition of mucosal membranes, systemic immune strength, virulence of the infectious agent and the morphology of paranasal sinuses. Medications used in acute rhinosinusitis provide symptomatic treatment, their effect being aimed at reduction of inflammation and swelling. Products obtained from medicinal plants may provide an alternative to these medications. In vitro studies have shown that these products demonstrate anti-inflammatory, immunostimulating, anti-edemic, and antiviral effects. With the market placement of Sinupret extract, the armamentarium of therapeutic has been extended by a concentrated product characterized by strength comparable to that of synthetic analgesic and anti-inflammatory drug as well as by additional, documented antiviral effect. The article discusses the composition of Sinupret extract, the mechanisms of action of its active substances, and the results of preclinical and clinical studies of Sinupret and Sinupret extract.
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