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Journal
2018 | 67 | 1 | 131-137
Article title

Białko cacybp/sip i jego rola w organizacji cytoszkieletu

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Title variants
EN
Cacybp/sip protein and its role in cytoskeleton organization
Languages of publication
PL EN
Abstracts
PL
Białko CacyBP/SIP występuje w różnych komórkach i tkankach ssaków, a jego wysoki poziom notowany jest w mózgu, śledzionie, grasicy oraz w wielu nowotworach. CacyBP/SIP oddziałuje z wieloma białkami efektorowymi, w tym z białkami cytoszkieletu: aktyną, tubuliną, tropomiozyną. Wskazuje to, iż CacyBP/SIP bierze udział w procesach komórkowych, którym towarzyszą zmiany w organizacji cytoszkieletu zarówno w warunkach fizjologicznych jak też w różnych stanach chorobowych. W niniejszej pracy przedstawiono charakterystykę oddziaływania CacyBP/SIP z białkami cytoszkieletu oraz rolę tych interakcji w różnych procesach komórkowych.
EN
The CacyBP/SIP protein is present in different mammalian cells and tissues. Its particularly high level is observed in brain, spleen, thymus and in many cancers. CacyBP/SIP interacts with different targets including cytoskeletal proteins such as tubulin, actin, tropomyosin. This indicates that CacyBP/SIP is involved in cellular processes associated with changes in cytoskeleton organization under physiology and pathology. In the present work the characteristics of complexes formed between CacyBP/SIP and cytoskeletal proteins and the role of those interactions are presented.
Journal
Year
Volume
67
Issue
1
Pages
131-137
Physical description
Dates
published
2018
Contributors
author
  • Pracownia Białek Wiążących Wapń, Zakład Neurobiologii Molekularnej i Komórkowej, Instytut Biologii Doświadczalnej im. M. Nenckiego PAN, Pasteura 3, 02-093 Warszawa, Polska
  • Laboratory of Calcium Binding Proteins, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology PAS, 3 Pasteur Str., 02-093 Warsaw, Poland
  • Pracownia Białek Wiążących Wapń, Zakład Neurobiologii Molekularnej i Komórkowej, Instytut Biologii Doświadczalnej im. M. Nenckiego PAN, Pasteura 3, 02-093 Warszawa, Polska
  • Laboratory of Calcium Binding Proteins, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology PAS, 3 Pasteur Str., 02-093 Warsaw, Poland
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-ksv67p131kz
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