Immunosensoryczne funkcje nerwu błędnego

• Authors: Anna Kobrzycka , Konrad Rudnicki , Grzegorz Jabłoński , Marek Wieczorek

Title variants

EN

Immunosensory functions of the vagus nerve

• Languages of publication: PL EN

Abstracts

PL

Współczesne badania nad komunikacją neuroimmunologiczną pozwalają coraz lepiej zrozumieć odpowiedź odpornościową organizmu oraz zachowania człowieka i zwierząt w chorobie. Jedną z najważniejszych dróg tej komunikacji jest nerw błędny. Jego aferentne zakończenia zbierają informacje bezpośrednio, wykorzystując receptory dla cząsteczek sygnałowych układu odpornościowego oraz pośrednio dzięki komunikacji z innymi, wyspecjalizowanymi komórkami. Wskutek tych procesów ośrodkowy układ nerwowy otrzymuje informacje niezbędne do regulacji odpowiedzi odpornościowej, aktywności hormonalnej i zachowania. Celem niniejszego opracowania jest podsumowanie dotychczasowej wiedzy na temat procesów fizjologicznych pozwalających nerwowi błędnemu na pośredniczenie w komunikacji między pobudzonym układem odpornościowym a ośrodkowym układem nerwowym.

EN

Contemporary research on neuroimmune communication allowed us to expand on our understanding of the immune response as well as human and animals sickness behavior. One of the most important paths of communication is the vagus nerve. Its afferent endings gather information directly thanks to their receptors for signaling molecules of the immune system, as well as indirectly by communicating with other specialized cells. As a result, central nervous system collects information necessary for regulating the immune response, hormonal activity and behavior. The purpose of this work is to summarize our current knowledge on the physiological processes that allow the vagus nerve to mediate the communication between the immune system and the central nervous system.

Keywords

PL

immunomodulacja; nerw błędny; układ immunologiczny; układ nerwowy; zachowanie w chorobie

EN

immune system; immunomodulation; nervous system; sickness behavior; vagus nerve

• Journal: Kosmos
• Year: 2017
• Volume: 66
• Issue: 4
• Pages: 651-663

Dates

published

2017

Contributors

author

Anna Kobrzycka

• Katedra Neurobiologii, Wydział Biologii i Ochrony Środowiska, Uniwersytet Łódzki, Pomorska 141/143, 90-236 Łódź, Polska
• Department of Neurobiology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland

author

Konrad Rudnicki

• University of Antwerp, Faculty of Social Sciences, Department of Communication Science, 2000 Antwerp, Belgium, St-Jacobstraat 2

author

Grzegorz Jabłoński

• Katedra Fizjologii Zwierząt i Człowieka, Wydział Biologii, Uniwersytet Gdański, Wita Stwosza 59, 80-308 Gdańsk, Polska
• Department of Animal and Human Physiology, Faculty of Biology, University of Gdańsk, Wita Stwosza 59, 80-308 Gdańsk, Poland

author

Marek Wieczorek

• Katedra Neurobiologii, Wydział Biologii i Ochrony Środowiska, Uniwersytet Łódzki, Pomorska 141/143, 90-236 Łódź, Polska
• Department of Neurobiology, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland

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