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Journal
2016 | 65 | 1 | 17-22
Article title

Potencjał bioterapeutyczny technologii RNAi

Content
Title variants
EN
Biotherapeutic potential of RNAi technology
Languages of publication
PL EN
Abstracts
PL
W ciągu ostatnich lat zjawisko interferencji RNA (RNAi) stało się powszechnie wykorzystywane jako eksperymentalne narządzie do analizy genów oraz pełnionych przez nie funkcji. Wraz ze wzrostem wiedzy na temat molekularnych mechanizmów działania endogennego interferującego RNA, małe interferujące RNA (siRNA), mogą pojawić się jako grupa innowacyjnych bioleków stosowanych do leczenia wielu chorób m.in. chorób nowotworowych. Poznanie i zrozumienie szlaków molekularnych istotnych w procesie nowotworzenia stwarza możliwości dla terapii nowotworowej wykorzystującej mechanizm RNAi. Nowe terapie w leczeniu nowotworów są niezbędne, a wykorzystanie małych interferujących RNA może stanowić realną strategię.
EN
In the last few years, RNA interference (RNAi) has become widely used as an experimental tool for the analyses of genes and their functions. With increasing knowledge about the molecular mechanisms of function of endogenous RNA interference, small interfering RNA (siRNA), may occur as innovative bio-drugs for treatment of diseases such as cancer. Knowledge and understanding of the molecular pathways important for carcinogenesis create opportunities for cancer therapy using RNAi mechanism. New therapies are essential for tumors treatment, and small interfering RNAs may provide a viable strategy.
Journal
Year
Volume
65
Issue
1
Pages
17-22
Physical description
Dates
published
2016
Contributors
  • Instytut Biotechnologii Stosowanej i Nauk Podstawowych, Uniwersytet Rzeszowski, Werynia 502; 36-100 Kolbuszowa, Polska
  • Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland
  • Centrum Biotechnologii Stosowanej i Nauk Podstawowych, Uniwersytet Rzeszowski, Werynia 502; 36-100 Kolbuszowa, Polska
  • Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland
  • Wydział Medyczny, Przyrodnioczo-Medyczne Centrum Badań Innowacyjnych, Uniwersytet Rzeszowski, Warzywna 1a; 35-310 Rzeszów, Polska
  • Faculty of Medicine, Centre for Innovative Research in Medical and Natural Sciences, University of Rzeszow, Warzywna 1a; 35-310 Rzeszów, Poland
  • Instytut Biotechnologii Stosowanej i Nauk Podstawowych, Uniwersytet Rzeszowski, Werynia 502; 36-100 Kolbuszowa, Polska
  • Institute of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland
  • Centrum Biotechnologii Stosowanej i Nauk Podstawowych, Uniwersytet Rzeszowski, Werynia 502; 36-100 Kolbuszowa, Polska
  • Centre of Applied Biotechnology and Basic Sciences, University of Rzeszow, Werynia 502, 36-100 Kolbuszowa, Poland
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-ksv65p17kz
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