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2014 | 63 | 2 | 173-180
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Human sleep and its regulation

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Human sleep and its regulation
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Każdą noc poświęcamy na sen. Obserwując osobę śpiącą, można błędnie sądzić, że sen jest czasem bezczynności dla ciała i mózgu. Jednak przypuszczenie to jest dalekie od prawdy. Podczas snu mózg tętni aktywnością i co więcej pojawiają się wtedy charakterystyczne tylko dla snu korowe oscylacje jego czynności bioelektrycznej. W artykule tym omawiamy metody wykorzystane do poznania aktywności mózgowej podczas snu, koncentrując się na oscylacji korowej, którą nazywamy falą wolną. Fale wolne cechują się niską częstotliwością i wysoką amplitudą, która odzwierciedla procesy homeostazy snu. Innymi słowy, ich amplituda jest miarą ilości wcześniejszego snu i/lub czuwania, wzrastając z czasem czuwania, a zmniejszając się podczas snu. Wyjaśniamy w jaki sposób te fale zostały użyte w modelu homeostatycznej regulacji snu. W końcu, przedstawiamy kilka fundamentalnych teorii o funkcjach snu.
Every night we give ourselves over to sleep. Observing a sleeping person one might mistakenly think that sleep is a time of inactivity for the body and brain. However, this is far from true. During sleep the brain is buzzing with activity and cortical oscillations emerge that can only be seen while asleep. In this article we discuss methods used to capture brain activity during sleep, and focus on a cortical oscillation called the slow wave. Slow waves are low frequency high amplitude waves that reflect the sleep homeostatic processes - they track the amount of prior sleep and wakefulness, increasing with time awake and decreasing during sleep. We discuss how these waves have been used to model the homeostatic sleep process. Finally, we conclude by giving an overview of a few of the most prominent theories about the functions of sleep.
Physical description
  • Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
  • Institute of Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland
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