Charakterystyka gleju drosophila melanogaster - porównanie do gleju kręgowców

• Authors: Jolanta Górska-Andrzejak

Title variants

EN

Characterization of Drosophila melanogaster glia in comparison with vertebrate glia

• Languages of publication: PL EN

Abstracts

PL

W układzie nerwowym muszki owocowej, Drosophila melanogaster liczba komórek glejowych w stosunku do liczby neuronów jest znacznie mniejsza niż w układzie nerwowym kręgowców. Mechanizm ukierunkowania komórek macierzystych na szlak rozwojowy gleju także jest inny, jednakże podobnie jak u kręgowców, populacja komórek glejowych D. melanogaster jest populacją heterogenną. W jej skład wchodzą cztery podstawowe typy komórek wyspecjalizowane do pełnienia różnych funkcji. Jest to glej powierzchniowy, glej korowy i glej neuropilu w centralnym układzie nerwowym (CUN), oraz glej peryferyczny w obwodowym układzie nerwowym (OUN). Pod względem morfologii i funkcji komórki te wykazują duże podobieństwo do odpowiednich typów komórek glejowych kręgowców. Podobieństwo to powstało niezależnie w toku ewolucji, w wyniku specjalizacji do pełnienia określonych funkcji. W niniejszym artykule przedstawiono porównanie poszczególnych typów i podtypów komórek glejowych D. melanogaster do gleju kręgowców: astrocytów, oligodendrocytów, mikrogleju i komórek Schwanna.

EN

In comparison with vertebrates, the fruit fly, Drosophila melanogaster, has fewer glial cells and much lower glia to neuron ratio. Glia of D. melanogaster is also specified by a different molecular mechanism of differentiation. However, just as vertebrates glia, it is specialized for distinct functions depending on its type. There are four main types of glia in D. melanogaster nervous system: the surface glia, the cortex glia and the neuropil glia in CNS, as well as the peripheral glia in PNS. Based on morphological and/or functional similarities (that have arisen independently and do not represent homologies), one can conclude that D. melanogaster glia share many common features with vertebrate glia. This article characterizes different types and sub-types of D. melanogaster glia in comparison with vertebrate astrocytes, oligodendrocytes, microglia and Schwann cells.

• Journal: Kosmos
• Year: 2013
• Volume: 62
• Issue: 4
• Pages: 535-546

Dates

published

2013

Contributors

author

Jolanta Górska-Andrzejak

• Uniwersytet Jagielloński, Instytut Zoologii, Zakład Biologii i Obrazowania Komórki, Gronostajowa 9, 30-387 Kraków, Polska

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