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Journal

2012 | 61 | 1 | 93-103

Article title

Alkohol a stres oksydacyjny

Content

Title variants

EN
Alcohol and oxidative stress

Languages of publication

PL EN

Abstracts

PL
Etanol ma istotny wpływ na proces wytwarzania reaktywnych form tlenu, a tym samym na generowanie stresu oksydacyjnego. Dokonano charakterystyki RFT oraz opisano mechanizm ich powstawania. Oksydacyjnym uszkodzeniom ulegają białka, DNA i lipidy. Istotna rolę odgrywają reaktywne formy tlenu w procesach chorobotwórczych u osób przewlekle spożywających alkohol. Wśród chorób związanych z oddziaływaniem RFT i nadużywaniem alkoholu wyróżnia się: choroby wątroby, miażdżycę, nadciśnienie tętnicze, rozwój nowotworów, spadek odporności, zaburzenia funkcji seksualnych, a także przyspieszenie procesu starzenia się skóry. Organizm ochraniają antyoksydanty wewnątrzkomórkowe i zewnątrzkomórkowe.
EN
Ethanol significantly influences formation of reactive oxygen species (ROS) in cells, and thus generation therein of oxidative stress. At present, ROS and mechanisms of their formation and action are well characterized. Under the stress condition, proteins, DNA and lipids undergo oxidative damages. In persons consuming alcohol protractedly, ROS play an important role in etiology of pathogenic processes, in particular such as liver diseases, arteriosclerosis, arterial hypertension, development of tumors, decrease in immunity, disorder of sexual functions, and acceleration of skin aging. Intracellular and outside antioxidants help to protect organism from the oxidative stress.

Keywords

Journal

Year

Volume

61

Issue

1

Pages

93-103

Physical description

Dates

published
2012

Contributors

  • Zakład Fizjologii Zwierząt, Instytut Biologii, Uniwersytet Jana Kochanowskiego w Kielcach, Świętokrzyska 15, 25-406 Kielce, Polska
  • Samodzielny Publiczny Zakład Opieki Zdrowotnej, Miejski Ośrodek Profilaktyki i Terapii Uzależnień im. bł. Rafała Chylińskiego w Łodzi, Niciarniana 41, 92-320 Łódź, Polska
author
  • Katedra Zdrowia Publicznego, Wyższa Szkoła Umiejętności w Kielcach im. Stanisława Staszica, Olszewskiego 6, 25-663 Kielce

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Publication order reference

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bwmeta1.element.bwnjournal-article-ksv61p93kz
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