Alkohol a niektóre enzymy

• Authors: Bożena Witek , Ewa Kwiecień-Błońska , Szymon Zmorzyński

Title variants

EN

Alcohol and enzymes

• Languages of publication: PL EN

Abstracts

PL

Alkohol etylowy może zmieniać funkcje poszczególnych organów i układów wewnętrznych a także strukturę i funkcje komórek. Organem najbardziej narażonym na toksyczne jego działanie jest wątroba. W hepatocytach 90% etanolu ulega enzymatycznemu utlenieniu do aldehydu octowego a następnie do kwasu octowego. Ostre i przewlekłe zatrucie etanolem prowadzi do nadmiernego nagromadzenia tam lipidów i do stłuszczenia wątroby. Alkoholowe zaburzenia metaboliczne wątroby i trzustki wywierają zróżnicowany wpływ na aktywność enzymów w tych narządach, w zależności od rodzaju enzymu i czasu trwania zatrucia etanolem.

EN

Ethyl alcohol may affect the structure and functions of cells, organs and whole organisms. The organ most strongly exposed to toxic ethanol expression is liver. In hepatocytes 90% of ethanol undergoes enzymatic oxidation to acetaldehyde, and then to acetic acid. Acute and chronic ethanol intoxication inhibits the biosynthesis of many enzymes, causes excessive accumulation of lipids in the liver, and in consequence its fatty degeneration. Alcoholic metabolic disorders in the liver and pancreas affect differently activity of enzymes in these organs, in dependence on the enzyme type and duration of ethanol intoxication.

• Journal: Kosmos
• Year: 2012
• Volume: 61
• Issue: 1
• Pages: 77-82

Dates

published

2012

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