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2010 | 59 | 1-2 | 9-16
Article title

Budowa przestrzenna i działanie rybosomu bakteryjnego. nagroda nobla z chemii 2009

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Content
Title variants
EN
The structure and function of the ribosome. Nobel Prize in chemistry 2009
Languages of publication
PL EN
Abstracts
EN
The Nobel prize in chemistry was awarded to Venkatraman Ramakrishnan, Thomas A. Steitz and Ada E. Yonath for their studies on the structure and function of the ribosome. These scientists used X-ray crystallography to determine the three dimensional structure of the bacterial ribosome at atomic resolution. The knowledge of the positions of atoms in such a large macromolecular complex helped to resolve its mechanism of action. Their studies confirmed that the ribosome is a ribozyme and exerts its catalytic power from the RNA and not proteins. This paves way to design novel antibiotics targeting the bacterial ribosome. Next step would be to determine a high resolution structure of the eukaryotic ribosome which is larger and more complicated than the prokaryotic one.
Keywords
Journal
Year
Volume
59
Issue
1-2
Pages
9-16
Physical description
Dates
published
2010
Contributors
  • Interdyscyplinarne Centrum Modelowania Matematycznego i Komputerowego, Pawińskiego 5A, 02-106 Warszawa, Polska
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-ksv59p9kz
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