Preferences help
enabled [disable] Abstract
Number of results
2010 | 59 | 3-4 | 497-512
Article title

O złożoności zegara biologicznego owadów, czyli jak narządy odmierzają czas

Title variants
Biological clockwork mechanisms in insects - how many clocks tick in their bodies?
Languages of publication
Insects display a rich variety of circadian behavioral rhythms. Many cellular and molecular processes also vary as a function of time of day. All these rhythms appear to be controlled by a common clock mechanism, which consists of molecular feedback loops that involve several clock genes and their proteins. The roles of many clock genes have been well established in the fruit fly, Drosophila melanogaster, and their orthologs have been found in other insects. Clock genes are expressed in the central nervous system and clock-positive neurons regulate behavioral rhythms in insects. In addition, clock genes are widely expressed in peripheral tissues implying that they perform important physiological functions. In this paper, the recent progress in the understanding of the biological clock mechanism and its functions in insect life are reviewed. How our knowledge about circadian systems of insects has developed during the past decade is also discussed.
Physical description
  • Allada R., Chung B. Y., 2010. Circadian organization of behavior and physiology in Drosophila. Annu. Rev. Physiol. 72, 605-24.
  • Beaver L. M., Gvakharia B. O., VOLLINTINE T. S., Hege D. M., Stanewsky R., Giebultowicz J. M., 2002. Loss of circadian clock function decreases reproductive fitness in males of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 99, 2134-2139.
  • Bebas P., Cymborowski B., Giebultowicz J. M., 2001. Circadian rhythm of sperm release in males of the cotton leafworm Spodoptera littoralis: in vivo and vitro studies. J. Insect Physiol. 47, 859-866.
  • Bloch G., 2010. The social clock of the honeybee. J. Biol. Rhythms 25, 307-317.
  • Cuninkova L., Brown S. A., 2008. Peripheral circadian oscillators: interesting mechanisms and powerful tools. Ann. NY Acad. Sci. 1129, 358-370.
  • Dibner C., Schibler U., Albrecht U., 2010. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu. Rev. Physiol. 72, 517-549.
  • Giebultowicz J. M., 1999. Insect circadian rhythms: Is it all in their heads? J. Insect Physiol. 45, 791-800.
  • Giebultowicz J. M., 2001. Peripheral clocks and their role in circadian timing: insights from insects. Philos. Trans. R. Soc. Lond. B Biol. Sci. 356, 1791-1799.
  • Giebultowicz J. M., Bebas P., 2005. Functions of biological clocks in insect physiology and reproduction: Practical aspects. Pestycydy/Pesticides 4, 77-90.
  • Giebultowicz J. M., Hege D. M., 1997. Circadian clock in Malpighian tubules. Nature 386, 664.
  • Giebultowicz J. M., Riemann J. G., Raina A. K., Ridgway R. L., 1989. Circadian system controlling release of sperm in the insect testes. Science 245, 1098-1100.
  • Giebultowicz J. M., Stanewsky R., Hall J. C., Hege D. M., 2000. Transplanted Drosophila excretory tubules maintain circadian clock cycling out of phase with the host. Curr. Biol. 10, 107-110.
  • Gvakharia B. O., Kilgore J. A., Bebas P., Giebultowicz, J. M., 2000. Temporal and spatial expression of the period gene in the reproductive system of the codling moth. J. Biol. Rhythms 15, 27-35.
  • Hege D. M., Stanewsky R., Hall J. C., Giebultowicz J. M., 1997. Rhythmic expression of a PER-reporter in the Malpighian tubules of decapitated Drosophila: evidence for a brain-independent circadian clock. J. Biol. Rhythms 12, 300-308.
  • Homberg U., Reischig T., Stengl M., 2003. Neural organization of the circadian system of the cockroach Leucophaea maderae. Chronobiol. Int. 20, 577-591.
  • Howlader G., Sharma V. K., 2006. Circadian regulation of egg-laying behavior in fruit flies Drosophila melanogaster. J. Insect Physiol. 52, 779-785.
  • Ito C., Goto S. G., Shiga S., Tomioka K., Numata H., 2008. Peripheral circadian clock for the cuticle deposition rhythm in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 105, 8446-8451.
  • Ivanchenko M., Stanewsky R., Giebultowicz J. M., 2001. Circadian photoreception in Drosophila: functions of cryptochrome in peripheral and central clocks. J. Biol. Rhythms 16, 205-215.
  • Kotwica J., Bebas P., Gvakharia B. O., Giebultowicz J. M., 2009. RNA interference of the period gene affects the rhythm of sperm release in moths. J. Biol. Rhythms 24, 25-34.
  • Kotwica J., Joachimiak E., Polanska M. A., Giebultowicz J. M., Bebas P., 2010. Diurnal rhythm in expression and release of yolk protein in the testis of Spodoptera littoralis (Lepidoptera: Noctuidae). Insect Biochem. Mol. Biol., w druku.
  • Krishnan P., Dryer S. E., Hardin P. E., 2005. Measuring circadian rhythms in olfaction using electroantennograms. Methods Enzymol. 393, 495-508.
  • Kuhlman S. J., Mackey S. R., Duffy J. F., 2007. Biological Rhythms Workshop I: introduction to chronobiology. Cold Spring Harb. Symp. Quant. Biol. 72, 1-6.
  • Liu X., Lorenz L., Yu Q., Hall J. C., Rosbash M., 1988. Spatial and temporal expression of the period gene in Drosophila melanogaster. Genes Dev. 2, 228-238.
  • Markova E. P., Ueda H., Sakamoto K., Oishi K., Shimada T., Takeda M., 2003. Cloning of Cyc (Bmal1) homolog in Bombyx mori: structural analysis and tissue specific distributions. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 134, 535-542.
  • Merlin C., Lucas P., Rochat D., Francois M. C., Maibeche-Coisne M., Jacquin-Joly E., 2007. An antennal circadian clock and circadian rhythms in peripheral pheromone reception in the moth Spodoptera littoralis. J. Biol. Rhythms 22, 502-514.
  • Nitabach M. N., Taghert P. H., 2008. Organization of the Drosophila circadian control circuit. Curr. Biol. 18, R84-93.
  • Reppert S. M., 2007. The ancestral circadian clock of monarch butterflies: role in time-compensated sun compass orientation. Cold Spring Harb. Symp. Quant. Biol. 72, 113-118.
  • Rosbash M., Bradley S., Kadener S., Li Y., Luo W., Menet J. S., Nagoshi E., Palm K., Schoer R., Shang Y., Tang C. H., 2007. Transcriptional feedback and definition of the circadian pacemaker in Drosophila and animals. Cold Spring Harb. Symp. Quant. Biol. 72, 75-83.
  • Sandrelli F., Costa R., Kyriacou C. P., Rosato E., 2008. Comparative analysis of circadian clock genes in insects. Insect Mol. Biol. 17, 447-463.
  • Sauman I., Reppert S. M., 1998. Brain control of embryonic circadian rhythms in the silkmoth Antheraea pernyi. Neuron 20, 741-748.
  • Schuckel J., Siwicki K. K., Stengl M., 2007. Putative circadian pacemaker cells in the antenna of the hawkmoth Manduca sexta. Cell Tissue Res. 330, 271-278.
  • Shao Q. M., Bembenek J., Trang Le T. D., Hiragaki S., Takeda M., 2008. Molecular structure, expression patterns, and localization of the circadian transcription modulator CYCLE in the cricket, Dianemobius nigrofasciatus. J. Insect Physiol. 54, 403-413.
  • Siwicki K. K., Eastman C., Petersen G., Rosbash M., Hall J. C., 1988. Antibodies to the period gene product of Drosophila reveal diverse tissue distribution and rhythmic changes in the visual system. Neuron 1, 141-150.
  • Stanewsky R., 2003. Genetic analysis of the circadian system in Drosophila melanogaster and mammals. J. Neurobiol. 54, 111-147.
  • Tamai T. K., Vardhanabhuti V., Arthur S., Foulkes N. S., Whitmore D., 2003. Flies and fish: birds of a feather. J. Neuroendocrinol. 15, 344-349.
  • Tomioka K., Abdelsalam S., 2004. Circadian organization in hemimetabolous insects. Zool. Sci. 21, 1153-1162.
  • Uryu O., Tomioka K., 2010. Circadian oscillations outside the optic lobe in the cricket Gryllus bimaculatus. J. Insect Physiol. 56, 1284-1290.
  • Vafopoulou X., Terry K. L., Steel C. G., 2010. The circadian timing system in the brain of the fifth larval instar of Rhodnius prolixus (Hemiptera). J. Comp. Neurol. 518, 1264-1282.
  • Vansteensel M. J., Michel S., Meijer J. H., 2008. Organization of cell and tissue circadian pacemakers: a comparison among species. Brain. Res. Rev. 58, 18-47.
  • Wise S., Davis N. T., Tyndale E., Noveral J., Folwell M. G., Bedian V., Emery I. F., Siwicki K. K., 2002. Neuroanatomical studies of period gene expression in the hawkmoth, Manduca sexta. J. Comp. Neurol. 447, 366-380.
  • Xu K., Zheng X., Sehgal A., 2008. Regulation of feeding and metabolism by neuronal and peripheral clocks in Drosophila. Cell Metab. 8, 289-300.
  • Yuan Q., Metterville D., Briscoe A. D., Reppert S. M., 2007. Insect cryptochromes: gene duplication and loss define diverse ways to construct insect circadian clocks. Mol. Biol. Evol. 24, 948-955.
  • Zhang E. E., Kay S. A., 2010. Clocks not winding down: unravelling circadian networks. Nat. Rev. Mol. Cell Biol. 11, 764-776.
Document Type
Publication order reference
YADDA identifier
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.