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Journal
2010 | 59 | 3-4 | 297-304
Article title

Grelina - hormon żarłoczności?

Content
Title variants
EN
Is ghrelin a hormone of gluttony?
Languages of publication
PL EN
Abstracts
EN
The hypothalamus plays a major role in the control of energy balance and food intake. It integrates hormonal, neural and metabolic signals pertaining to body-energy status and, in response to these inputs, coordinates adaptive alterations of energy intake and expenditure. Ghrelin, a peptide produced mainly in the stomach, stimulates feeding and fat deposition. Plasma level of ghrelin is increased under negative energy balance. Ghrelin strongly and dose-dependently stimulates growth hormone release, as well as a release of prolactin and adrenocorticotropin. Moreover, pretreatment with ghrelin exhibits protective effect against damage evoked by different noxious agents. This protective effect has been found, between others, in the heart, kidney, brain, stomach, intestine and the pancreas. Apart from protective effect, administration of ghrelin exhibits also therapeutic effect in experimental heart infarct, acute pancreatitis or gastric and duodenal ulcers.
Keywords
Journal
Year
Volume
59
Issue
3-4
Pages
297-304
Physical description
Contributors
  • Zakład Fizjologii Klinicznej, Katedra Fizjologii, Collegium Medicum, Uniwersytet Jagielloński, Grzegórzecka 16, 31-531 Kraków, Polska
  • Zakład Fizjologii Klinicznej, Katedra Fizjologii, Collegium Medicum, Uniwersytet Jagielloński, Grzegórzecka 16, 31-531 Kraków, Polska
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-ksv59p297kz
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