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2008 | 57 | 1-2 | 93-102
Article title

Melatonina u ssaków - związek o wielu funkcjach

Title variants
Melatonin in mammals - a multipurpose compound
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Melatonin is an indoloamine of widespread distribution in the plant and animal kingdoms. N-acetyl-5-methoxytryptamine is regarded as a hormone as well as paracoid and autocoid. In mammals, melatonin is mainly synthesized by the pineal gland and its biosynthesis exhibits a circadian rhythm which depends on the light conditions and is controlled by the endogenous biological clock (SCN). This compound exerts a number of receptor mediated actions including chronobiotic effects and very likely has a property to increase the activity of antioxidative enzymes. Melatonin also is able to reduce the oxidative stress in a receptor independent way through free radicals' scavenging. People commonly use melatonin as a drug reducing jet lag, insomnia and in the supportive therapy of cancer.
Physical description
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