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Journal
2007 | 56 | 3-4 | 327-334
Article title

Biokataliza

Content
Title variants
EN
Biocatalysis
Languages of publication
PL EN
Abstracts
EN
The use of enzymes, either derived from natural sources or generated through directed evolution methods, has increased significantly over the past decades. Replacing the aqueous milieu with organic solvents, ionic liquids, supercritical fluids, fluoro-hydrocarbons etc. enables biocatalysis to increase the chemo-, regio- and enantio-specificity and catalytic efficiency of many enzymes. Combinatorial biocata­lysis uses enzymes and whole microbial cells to generate libraries of derivatives of many compounds. Enzyme catalytic promiscuity, i.e. capability of catalyzing new reactions of new substrates, has been recognized as a valuable research and synthesis tool. The systematic organization of information pertaining to enzymes' function and structure is of great importance for further development of biocatalysis.
Keywords
Journal
Year
Volume
56
Issue
3-4
Pages
327-334
Physical description
Dates
published
2007
Contributors
  • Instytut Biochemii Technicznej, Politechnika Łódzka, Stefanowskiego 4/10, 90-924 Łódź, Polska
  • Instytut Biochemii Technicznej, Politechnika Łódzka, Stefanowskiego 4/10, 90-924 Łódź, Polska
  • Instytut Biochemii Technicznej, Politechnika Łódzka, Stefanowskiego 4/10, 90-924 Łódź, Polska
References
  • Altreuter D. A., Clark D. S., 1999, Combinatorial biocatalysis: taking the lead from Nature. Curr. Opin. Biotechnol. 10, 130-136.
  • Castro G. R., Knubovets T., 2003. Homogeneous biocatalysisis in organic solvents and water-organic mixtures. Crit.. Rev. Biotechnol. 23, 195-231.
  • Hult K., Berglund P., 2007, Enzyme promiscuity: mechanism and applications. Trends Biotechnol. 25, 231-238.
  • Kaur J., Sharma R., 2006. Directed evolution: an approach to engineer enzymes. Crit. Rev. Biotechnol. 26, 165-199.
  • Reents R., Jeyaraj D. A., Waldmann H., 2002. Enzymatically cleavable linker groups in polymer-supported synthesis. Drug Discov. Today 7, 71-74.
  • Wackett L. P., 2004. Novel biocatalysis by database mining. Curr. Opin. Biotechnol. 15, 280-284.
  • Yu G., Xue Y., Xu W., Zhang J., Xue C. H., 2007. Stability and activity of lipase in subcritical 1,1,1,2-tetrafluoroethane (R134a). J. Ind. Microbiol. Biotechnol. 34, 793-798.
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-ksv56p327kz
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