Dimer αγ białka G - cząsteczka sygnałowa

• Authors: Hanna Fabczak , Katarzyna Sobierajska , Stanisław Fabczak

Title variants

EN

Dimer βγ of G protein - signaling molecule

• Languages of publication: PL EN

Abstracts

EN

Summary The extracellular signals received by receptors with seven membrane-spanning regions that activate the G proteins, are routed to several distinct intracellular pathways. The G proteins consist of two functional units, Gα subunit, that binds guanine nucleotides and Gβγ dimer that functions as a single unit. The regulation of signal transduction by the Gβγ complex at different protein interfaces: subunit - subunit, receptor - G protein, and Gβγ - effector, are reviewed. Gβγ dimer regulates over twelve cellular effectors including phospholipase-β, adenyl cyclases, ion channels and G-protein coupled receptor kinases, which control a broad range of cellular processes.

• Journal: Kosmos
• Year: 2004
• Volume: 53
• Issue: 3-4
• Pages: 355-372

Dates

published

2004

Contributors

author

Hanna Fabczak

• Zakład Biologii Komórki Instytut Biologii Doświadczalnej im. Nenckiego PAN, Pasteura 3, 02-093 Warszawa, Polska

author

Katarzyna Sobierajska

• Zakład Biologii Komórki Instytut Biologii Doświadczalnej im. Nenckiego PAN, Pasteura 3, 02-093 Warszawa, Polska

author

Stanisław Fabczak

• Zakład Biologii Komórki Instytut Biologii Doświadczalnej im. Nenckiego PAN, Pasteura 3, 02-093 Warszawa, Polska

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