Budowa i funkcje białek błony lizosomalnej

• Authors: Katarzyna Roszek , Jadwiga Gniot-Szulżycka

Title variants

EN

Structure and functioning of lysosomal membrane proteins

• Languages of publication: PL EN

Abstracts

EN

Summary The lysosomal membrane delimits the interial part of lysosomes containing the enzymes capable of degrading practically all cellular macromolecules, and actively participates as well in establishing an efficient environment for the degradation processes. 1. H+-ATPase - the main membrane protein complex ensures the low pH environment needed for efficient activity of lysosomal hydrolases. 2. Glycoproteins lamp2a are involved in specific degradation of proteins containing the KFERQ sequence (chaperone mediated autophagy) under condition of stress and starvation. 3. Specific lysosomal membrane proteins participate in export from and import to of low molecular weight compounds such as amino acids, dipeptides, sugars, nucleosides, or ions.

• Journal: Kosmos
• Year: 2003
• Volume: 52
• Issue: 2-3
• Pages: 173-184

Dates

published

2003

Contributors

author

Katarzyna Roszek

• Zakład Biochemii, Wydział Biologii i Nauk o Ziemi, Instytut Biologii Ogólnej i Molekularnej, Uniwersytet Mikołaja Kopernika, Gagarina 7, 87-100 Toruń, Polska

author

Jadwiga Gniot-Szulżycka

• Zakład Biochemii, Wydział Biologii i Nauk o Ziemi, Instytut Biologii Ogólnej i Molekularnej, Uniwersytet Mikołaja Kopernika, Gagarina 7, 87-100 Toruń, Polska

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