Różnice międzypłciowe w częstości i ekspresji autyzmu1
Sex differences in the incidence and expression of autism
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Summary Autism is a pervasive developmental disorder that occurs more frequently in boys than in girls. Though this phenomenon is widely known, very few studies focused on the relationship between sex and autism. It may be supposed that there are genetic factors related to sex differences in the incidence of autism. Some genetic pathologies specific for males and related to autism, such as fragile chromosome X, have been identified. Little is also known about the relationship of sex and the expression and the severity of traits associated with autism. It was found that during the early stages of life, girls were rated to be less severely autistic than boys on several measures of social development: communication, initiating social play, and seeking comfort in relations with an other person. Later on these relations were reversed. Complete interpretation of the observed differences is not possible before more data are collected.
- AMERICAN PSYCHIATRIC ASSOCIATION, 1994. Diagnostic and statistical manual of mental disorders. Washington, DC.
- BAILEY A. J., BOLTON P., BUTLER L., LECOUTEUR A.,MURPHY M., SCOTT S., WEBB T., RUTTER M., 1993. Prevalence of the fragile X anomaly amongst autistic twins and singletons. J. Child Psychol. Psychiatry 34, 673-688.
- BORDEN M. C., OLLEDICK T. H., 1994. An examination of the validity of social subtypes in autism. J. Autism Dev. Disord. 24, 23-37.
- BRYSON S.E., CLARK B. S., SMITH I. M., 1988. First report of a Canadian epidemiological study of autistic syndromes. J. Child Psychol. Psychiat. 29, 433-446.
- COHEN I. L., VIETZE P. M., SUDHALTER V., JENKINS E. C., BROWN W. T., 1989. Parent-child dyadic gaze patterns in fragile X males with autistic disorder. J. Child Psychol. Psychiat. 30, 845-856.
- CONSTANTINO J. N., 2002. Genetic structure of gender differences in susceptibility to autistic traits. Streszczenie doniesienia przedstawionego podczas Annual Meeting of the AMERICAN Academy of Child and Adolescent Psychiatry, 2002.
- DEB S., PRASAD K. B. G., 1994. The prevalence of autistic disorder among children with a learning disability. Br. J. Psychiatry 165, 395-399.
- EHLERS S., GILLBERG CH., 1993. The epidemiology of Asperger syndrome. A total population study. J. Child Psychol. Psychiatry 34, 1327-1350.
- GAGE F. G., 2002. The stem cell debate: opportunity for a dialogue. [W:] Vision of the brain: a progress report on brain research. The Dana Alliance for Brain Inititives 5-40.
- GILLBERG C., WAHLSTROM J., 1985. Chromosome abnormalities in infantile autism and other childhood psychoses: a population study of 66 cases. Dev. Med. Child Neurol. 27, 293-304.
- GILLBERG C., STEFFENBURG S., SCHAUMANN H., 1991. Is autism more common now than ten years ago? Br. J. Psychiatry 158, 403-409.
- HONDA H., SHIMIZU Y., MISUMI K., NIMI M., OHASHI Y., 1996. Cumulative incidence and prevalence of childhood autism in children in Japan. Br. J. Psychiatry 169, 228-235.
- KIMURA D., 1999. Sex and cognition. Cambridge, Massachusetts, A Bradford Book, The MIT Press.
- KLIN A., VOLKMAR F. R., 1997. Asperger´s syndrome. [W:] Handbook of autism and pervasive developmental disorders. COHEN D. J., VOLKMAR F. R. (red.). New York: John Wiley & Sons, 94-122.
- LOLRD C., SCHOPLER E., REVICKI D., 1982. Sex differences in autism. J. Autism Dev. Disord. 12, 317-330.
- KONSTANTEAREAS M. M., HOMATIDIS S., BUSCH J., 1989. Cognitive, communication, and social differences between autistic boys and girls. J. Appl. Dev. Psychol. 10, 411-424.
- MCLENNAN J. D., LOLRD C., SCHOPLER E., 1993. Sex differences in higher functioning people with autism. J. Autism Dev. Disord., 23, 217-227.
- PIVEN J., GAYLE J., LANDA R., WZOREK M., FOLSTEIN S., 1991. The prevalence of the fragile X in a sample of autistic individuals diagnosed using a standardised interview. J. Am. Acad. Child Adolesc. Psychiat. 30, 825-830.
- SHAO J., WOLPERT C. M ., RAIFORD K. L., MENOLD M. M., DONNELLY S. L., RAVAN S. A., BASS M. P., MCCLAIN C., VONWENDT L., VANCE J. M., ABRAMSON R. H.,WRIGHT H. H., ASHLEY-KOCH GILBERT J. R., DELONG R. G., CUCCARO M. L., PERICAK-VANCE M.A., 2002. Genomic screen and follow-up analysis for autistic disorder. Am. J. Med. Genet. 114, 99-105.
- SCHOPLER E., 1996. Are autism and Asperger syndrome (AS) different labels or different disabilities? J. Autism Dev. Disord. 26, 109-110.
- STEFFENBURG S., GILLBERG C., 1986. Autism and autistic- like conditions in Swedish rural and urban areas: a population study. Br. J. Psychiatry 149, 81-87.
- TSAI L., STEWART M. A., AUGUST G., 1981. Implication of sex differences in the familial transmission of infantile autism. J. Autism Dev. Disord. 11, 165-173.
- WING L., 1981. Asperger´s syndrome: a clinical account. Psychol. Med. 11, 115-129.
- WING L., GOULD J., 1979. Severe impairment of social interaction and associated abnormalities in children: epidemiology and classification. J. Autism Dev. Disord. 9, 11-29.
- WORLD HEALTH ORGANIZATION, 1992. Manual of the international statistical classification of the diseases and related health problems. Geneva.
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