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Journal

2003 | 52 | 1 | 105-112

Article title

Zaburzenia obsesyjno-kompulsyjne a pĹeÄ pacjenta

Content

Title variants

EN
Obsessive-compulsive disorder and gender

Languages of publication

PL EN

Abstracts

EN
Summary Obsessive-compulsive disorder (OCD) is a neuropsychiatric illness due to damage of prefrontal cortex and basal ganglia. The lifetime prevalence rate of OCD is about 2.5% of the population. The rates in men and women are equal. The mean age of onset is in the mid-to-late twenties to early thirties, and it is slightly earlier in males´ population. OCD has two fundamental phenomenological characteristics: repetitive urges of thoughts or actions which patients experience as coming from their own mind but as alien to their will; and surges of unbearable anxiety which accompany either resistance to these compulsions or exposure to objects or thoughts which trigger the repetitive behaviour or cognitions. The cultural influence on the content of the obsessions has been noted in the epidemiological studies. The familial nature of OCD has been observed since several years and recent studies have provided limited evidence for the importance of genetic factors in the manifestation of obsessive-compulsive symptoms. Recent studies suggest gender-related clinical differences in the obsessive-compulsive disorder. The most prevalent obsession is concerned with contamination by dirt and/or germs. Washing is the accompanying compulsion and such patients may spend several hours daily washing their hands or cleaning their clothes. There are two main approaches to the treatment of OCD: psychological treatment and pharmacological treatment. Antidepressants afford a successful treatments for OCD but only those with potent effects on the serotonergic neurotransmitter systems appear to have antiobsessional efficacy.

Keywords

Journal

Year

Volume

52

Issue

1

Pages

105-112

Physical description

Dates

published
2003

Contributors

  • Katedra i Klinika Psychiatrii Akademii Medycznej, KurpiĹ„skiego 19, 85-096 Bydgoszcz, Polska

References

  • AKSARAY G., YELKEN B., KAPTANOGLU C., OFLU S., OZALTIN M., 2001. Sexuality in women with obsessive-compulsive disorder. J. Sex. Marital Ther. 27, 273-277.
  • ALBERT V., PICCO C., MARINA G., FORNER F., AGUGLIA E., BOGETTO F., 2002. Phenomenology of patients with early and adults onset obsessive-compulsive disorder. Epidemiol. Psychiat. Soc. 11, 116-126.
  • ALSOBROOK J. P., ZOHAR A. H., 2002. Association between the COMT and obsessive-compulsive disorder in females but not males. Am. J. Med. Genet. 114, 116-120.
  • ALTEMUS M., PIGOTT T., L´HEUREUX F., DAVIS C. L., RUBINOW D. R., MURPHY D. L., GOLD P. W., 1993 CSF somatostatin in obsessive-compulsive disorder. Am. J. Psychiatry 150, 460-464.
  • BOGETTO F., VENTURELLO S., ALBERT U.,MAINA G., RAVIZZA L., 1999. Gender-related clinical differences in obsessive- compulsive disorder. Eur. Psychiatry 14, 434-441.
  • BORKOWSKA A., PILACZYĹƒSKA E., ARASZKIEWICZ A., RYBAKOWSKI J., 2002. WpĹ‚yw sertraliny na funkcje poznawcze u chorych z zespoĹ‚em natrÄ™ctw. Psych. Pol. 36, 289-295.
  • CAMARENA B., RINETTI G., CRUZ C., GOMEZ A., DE LA FUENTE J.R., NICOLINI H., 2001. Additional evidence that genetic variation of MAO- A gene supports a gender subtype in obsessive-compulsive disorder. Am. J. Med. Genet. 105, 279-282.
  • CHRISTENSON G. A., MCKENZIE T. B., MITCHELL J. E., 1994. Adult men and women with trichotillomania. A comparison of male and female characteristics. Psychosomatics 35, 142-149.
  • COFFEY B. J.,MIGUEL E.C., BIEDERMAN J., BAER L., RAUCH S. L., O´SULLIVAN R. L., SAVAGE C. R., PHILLIPS K., BORGMAN A., GREEN-LEIBOVITZ M. I., MOORE E., PARK K. S., JENIKE M. A., 1998. Tourette´s disorder with and without obsessice-compulsive disorder in adults: are they diffrent? J. Nerv. Ment. Dis. 186, 201-206.
  • ENOCH M. A., GREENBERG B. D., 2001. Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder. Biol. Psychiatry 49, 385-388.
  • GRABE H. J., MEYER C., HAPKE U., RUMPF H. J., FREYBERGER H. J., DILLING H., 2001. Lifetime comorbidity of obsessive- compulsive dosroder and subclinical obsessive- compulsive dosroder in Northern Gemany. Eur. Arch. Psychiatry Clin. Neurosci. 251, 130-135.
  • ICD-10, 1992. Klasyfikacja zaburzeĹ„ psychicznych i zaburzeĹ„ zachowania w ICD-10. Opisy kliniczne i wskazĂłwki diagnostyczne. UWM 'Vesalius' i Instytut Psychiatrii i Neurologii, KrakĂłw-Warszawa.
  • JOHN U., 2001. Lifetime comorbidity of obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in Northern Germany. Eur. Arch. Psychiatry Clin. Neurosci. 251, 130-135.
  • GROVE G., COPLAN J., MARGOLIN L., HOLLANDER E., 1996. The neuroanatomy of serotonin (5-HT) Dysregulation on obsessive-compulsive disorder. CNS Spekrum 1, 16-22.
  • HOLLANDER E., BANZAQUEN S. D., 1997. The obsessive- compulsive spectrum disorder. J. A. den Boer, H. G. M. Westenberg.
  • KIEJNA A., RYMASZEWSKA J., KANTORSKA-JANIEC M., TOKARSKI W., 2002. Epidemiologia zaburzeĹ„ obsesyjno- kompulsyjnych. Psych. Pol. 36, 539-548.
  • LENSI P., CASSANO G. B., CORREDDU G., RAVAGLI S., KUNNOVAC J. L., AKISKAL H. S., 1996. Obsessive-compulsive disorder. Familial - developmental history symptomatology, comorbidity, and course with special reference to gender-related differences. Br. J. Psychiatry 169, 101-107.
  • MAES M.,MELTZER H. Y., BOSMANS E., 1994. Psychoimmune investigation in obsessive-compulsive disorder: assays of plasma trensferrin, IL-2 and IL-6 receptor, and IL 1beta and IL-6 concentrations. Neuropsychobiology 30, 57-60.
  • MAGGINI C., AMPOLLINI P., GARBOLDI S., PEQLIZZA L. MARECHESI C., 2001. The Parma High school Epidemiology Survey: obsessive-compulsive symptoms. Acta Psychiatr. Scand. 103, 441-446.
  • MATSUNAGA H, KIRIIKE N,MATSUI T,MIYATA A, IWASAKI Y, FUJIMOTO K, KASAI S, KOJIMA M., 2000. Gender differences in social and interpersonal features and personality disorders among Japanese patients with obsessive-compulsive disorder. Compr. Psychiatry 41, 266-272.
  • MCELROY S. L.,KECK P. E., PHILLIPS K. A., 1995. Kleptomania, compulsive buying and binge-eating disorder. J. Clin. Psychiatry 56, 14-26.
  • MONTELEONE P., CATAPANO F., TORTORELLA A., MAJ M., 1997. Cortisol response to d-fenfluramine in patients with obsessive-compulsive disorder and heathy subjects: evidence for a gender realted effect. Neuropsychobiology 36, 8-12.
  • MONTGOMERY S., ZOHAR J., 1999. Obsessive compulsive disorder. Martin Dunitz Ltd.
  • MUNDO E., BARREGI S. R., PIROLA R., BELLODI L., 1999. Efect of acute intravenous clomipramine and antuobsessional response to proserotonergic drugs: is gender a predictive variable? Biol. Psychiatry 45, 290-294.
  • NOSHIRVANI H. F., KASVIKIS Y., MARKS I.M., TSAKIRIS F., MONTEIRO W. O., 1991. Gender-divergent aetiological factors in obsessive-compulsive disorder. Br. J. Psychiatry 158, 260-263.
  • OKASHA A., SAAD A.,KHALIL A.H., ELDAWLA A. S., YEHIA N., 1994. Phenomenology of obsessive-compulsive disorder: A transkultural study. Compr. Psychiatry 35, 191-197.
  • RASMUSSEN S., EISEN J. L., 1992. The epidemiology and clinical features of obsessive-compulsive disorder. Psychiatry Clin. North Am. 14, 743-758.
  • RAVIZZA L., MAINA G., BOGETTO F., 1997. Episodic and chronic obsessive-compulsive disorder. Depress. Anxiety 6, 154-158.
  • SANTANGELO S. L., PAULS D. L., GOLDSTEIN J. M., FARAONE S. V., TSUANG M. T., LECKMAN J. F., 1994. Tourette´s syndrome: what are the influences of gender and comorbid obsessive-compulsive disorder. J. Am. Acad. Child. Adolesc. Psychiatry 33, 795-804.
  • STEIN D. J., LUDIK J., 2000. A neural network of obsessive- compulsive disorder: modeling cognitive disinhibition and neurotransmitter dysfunction. Med. Hypotheses 55, 168-176.
  • ZOHAR J., 1999. Orbitofrontal cortex dysfunction in obsessive- compulsive disorder? Alternation learning in obsessive-compulsive disorder male-female comparisons. Eur. Neuropsychopharmacol. 9, 407-413.

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.bwnjournal-article-ksv52p105kz
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