PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2002 | 51 | 3 | 353-364
Article title

Integrony

Content
Title variants
EN
Integrons
Languages of publication
PL EN
Abstracts
EN
Summary Accumulation of antibiotic resistance among pathogenic bacteria has called attention to horizontal gene transfer that involves plasmids and transpozons. Integrons, usually placed on mobile genome elements, are very deeply engaged in the process of origin of multiple-drug-resistant strains. Integrons are genetic elements that contain determinants of the components of the site-specific recombination system that recognizes and captures mobile gene cassettes. More than 70 different antibiotic resistance genes covering most classes of antimicrobials presently in use have been detected in gene cassettes. Integrons are frequently found in clinical and environmental strains of gram-negative rods. The discovery of super-integrons, i.e. genetic structures gathering gene cassettes in a huge number, led to the conception of genome cassettes capture as an element of a broader phenomenon of bacterial genome modification in response to changing environmental conditions.
Keywords
Journal
Year
Volume
51
Issue
3
Pages
353-364
Physical description
Dates
published
2002
References
  • BROWN H. J., STOKES H. W., HALL R. M., 1996. The integrons In0, In2, and In5 are defective transposon derivatives. J. Bacteriol. 178, 4429-4437.
  • CENTRÓN D., ROY P. H., 2002. Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion. Antimicrob. Agents Chemother. 46, 1402-1409.
  • COLLIS C. M., HALL R. M., 1995. Expression of antibiotic resistance genes in the integrated cassettes of integrons. Antimicrob. Agents Chemother. 39, 155-162.
  • COLLIS C. M., KIM M.-J., PARTRIDGE S. R., STOKES H. W., HALL R. M., 2002. Characterization of the class 3 integron and the site-specific recombination system it determines. J. Bacteriol. 184, 3017-3026.
  • DALSGAARD A., FORSLUND A., PETERSEN A., BROWN D. J., DIAS F., MONTEIRO S., MØLBAK K., AABY P., RODRIGUES A., SANDSTR×M A., 2000. Class 1 integron-borne, multiple-antibiotic resistance encoded by a 150 kilobase conjugative plasmid in epidemic Vibrio cholerae O1 strains isolated in Guinea-Bissau. J. Clin. Microbiol. 38, 3774-3779.
  • DZIADEK J., BRZOSTEK A., PARNIEWSKI P., JAWORSKI A., 1997. Retrony - retroelementy bakterii. Postępy Mikrobiologii 36, 1-17.
  • HANSSON K., SUNDSTRÖM L., PELLETIER A., ROY P. H., 2002. IntI2 integron integrase in Tn7. J. Bacteriol. 184, 1712-1721.
  • HALL R. M., COLLIS C. M., KIM M.-J., PARTRIDGE S. R., RECCHIA G. D., STOKES H. W., 1999. Mobile gene cassettes and integrons in evolution. Ann. NY Acad. Sci. 870, 68-80.
  • LIEBERT C. A., HALL R. M., SUMMERS A. O., 1999. Transposon Tn21, flagship of the floating genome. Microbiol. Mol. Biol. Rev. 63, 507-522.
  • NAAS T., MIKAMI Y., IMAI T., POIREL L., NORDMANN P., 2001. Characterization of In53, a class 1 plasmidand composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes. J. Bacteriol. 183, 235-249.
  • NESVERA J., HOCHMANNOVÁJ., PÁTEK M., 1998. An integron of class 1 is present on the plasmid pCG4 from Gram-positive bacterium Corynebacterium glutamicum. FEMS Microbiol. Lett. 169, 391-395.
  • NIELD B. S., HOLMES A. J., GILLINGS M. R., RECCHIA G. D., MABBUTT B. C., NEVALAINEN K. M. H., STOKES H. W., 2001. Recovery of new integron classes form environmental DNA. FEMS Microbiol. Lett. 195, 59-65.
  • PLOY M.-C., DENIS F., COURVALIN P., LAMBERT T., 2000. Molecular characterization of integrons in Acinetobacter baumannii: description of a hybrid class 2 integron. Antimicrob. Agents Chemother. 44, 2684-2688.
  • RECCHIA G. D., HALL R. M., 1995. Gene cassettes: a new class of mobile element. Microbiology 141, 3015-3027.
  • RECCHIA G. D., HALL R. M., 1997. Origins of the mobile gene cassettes found in integrons. Trends Microbiol. 5, 389-394.
  • ROWE-MAGNUS D. A., GUÉROUT A.-M., MAZEL D., 1999. Super-integrons. Res. Microbiol. 150, 641-651.
  • ROWE-MAGNUS D. A., GUEROUT A.-M., MAZEL D., 2002. Bacterial resistance evolution by recruitment of super-integron gene cassettes. Mol. Microbiol. 43, 1657-1669.
  • ROWE-MAGNUS D. A., GUEROUT A.-M., PLONCARD P., DYCHINCO B., DAVIES J., MAZEL D., 2001. The evolutionary history of chromosomal super-integrons provides an ancestry for multiresistant integrons. Proc. Natl. Acad. Sci. USA 98, 652-657.
  • VAISVILA R., MORGAN R. D., POSFAI J., RELEIGH E., 2001. Discovery and distribution of super-integrons among Pseudomonads. Mol. Microbiol. 42, 587-601.
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-ksv51p353kz
Identifiers
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.