EN
We have investigated single ionization of He by fast proton and antiproton using a QED approach. A field theoretical calculation gives the total cross-section of He in single ionization, from which it is seen that the projectile p^{+} or p^{-} gives almost the same values of cross-section. We have also compared our results with other theoretical and experimental results available in this context yet. Behaviour of the cross-section at a lower spectrum of projectile energy is discussed.