Proton and Deuteron Relaxation Study of Molecular Dynamics in Lysozyme Solutions

• Authors: J.F. Kakule , W.P. Węglarz , R.K. Shenoy , A.R. Sharp , H. Peemoeller
• Languages of publication: EN

Abstracts

EN

A nuclear magnetic resonance spin-lattice relaxation dispersion study of the relaxation of several magnetization components in both natural and deuterated lysozyme solutions was undertaken at 20°C. Proton and deuteron resonances were employed. The two-dimensional time evolution of the magnetization and the spin-spin relaxation were analyzed. In addition, an isotopic dilution study was performed at 5 and 30.6MHz. The results indicate that the water proton spin-lattice relaxation rate which arises from intermolecular relaxation between the water protons and the lysozyme protons represents a relatively strong relaxation mechanism. A model for the dynamics of the water molecules, consistent with the proton and deuteron dispersions as well as with the isotopic dilution results, is presented.

Keywords

EN

76.60.-k; 87.15.-v

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2000
• Volume: 98
• Issue: 1-2
• Pages: 131-152

Dates

published

2000-07

received

1999-08-23

(unknown)

2000-05-15

Contributors

author

J.F. Kakule

• Department of Physics, University of New Brunswick, Fredericton New Brunswick, E3B 5A3, Canada,

author

W.P. Węglarz

• H. Niewodniczański Institute of Nuclear Physics, Kraków, Poland,

author

R.K. Shenoy

• Department of Physics, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada

author

A.R. Sharp

• Department of Physics, University of New Brunswick, Fredericton New Brunswick, E3B 5A3, Canada,

author

H. Peemoeller

• Department of Physics, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada