Title variants
Languages of publication
Abstracts
Understanding of biological function requires knowledge both on structural and dynamical aspects. The aim of time-resolved X-ray diffraction is to combine structural and kinetic methods by monitoring structural or conformational changes within a single protein or assemblies of proteins during their biological action in real time. This requires (i) a powerful X-ray source, (ii) appropriate detectors capable of dealing with high local and total count rates and (iii) a suitable trigger mechanism. These aspects are briefly discussed with emphasis on light as trigger for initiation of structural or conformational changes. Examples are presented on muscle contraction, lipid phase transitions, the photocycle of bacteriorhodopsin and the application of Laue crystallography on the protein p21.
Journal
Year
Volume
Issue
Pages
103-120
Physical description
Dates
published
1992-07
Contributors
author
- EMBL c/o DESY, Notkestr. 82, W-2000 Hamburg 52, Germany
References
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-appv82z108kz