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2017 | 131 | 4 | 1102-1104
Article title

Effect of BSA Protein on the Contrast Properties of Magnetite Nanoparticles during MRI

Content
Title variants
Languages of publication
EN
Abstracts
EN
The aim of the study was to establish whether there is a significant change in the MRI contrast of magnetite nanoparticles, after BSA protein binding on the surface of particles. The rationale is the applicability of this feature in clinical practice for the tracking of specific proteins which are often associated with various pathologies. Contrast agents could bind to this specific marker, with the change in MRI contrast indicating the presence of pathology. We found that changes in relative contrast acquired at low-field MRI offer potential for the differentiation of magnetite nanoparticles with and without BSA protein. However, the variations in the transverse relaxation time (T₂) and transverse relaxivity (r₂), acquired at high-field MRI, were too small to be applicable for biomedical applications.
Keywords
EN
Year
Volume
131
Issue
4
Pages
1102-1104
Physical description
Dates
published
2017-04
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-appv131n4161kz
Identifiers
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