Preferences help
enabled [disable] Abstract
Number of results
2012 | 122 | 5 | 969-974
Article title

Optical Scanner for 3D Radiotherapy Polymer Gel Dosimetry

Title variants
Languages of publication
Sophisticated techniques employed in radiotherapy for irradiation of tumours require comprehensive dosimetry allowing for precise, high resolution measurements of radiation dose distribution in three dimensions and verification of treatment planning systems. Polymer gel dosimetry has been shown to be a unique technique for such the purpose. If exposed to ionizing radiation, radical polymerisation and crosslinking of monomeric components take place in a 3D polymer gel dosimeter, leading to the formation of large polymeric structures that scatter visible light. This feature allows for optical observation of the effects of the absorbed dose and its distribution. Presently, magnetic resonance imaging is employed most often for the analysis of the 3D polymer gel dosimeters. However, much attention is also being given to the development of optical computed tomography since this technique is hoped to serve as a substitute for expensive and not easily available magnetic resonance imaging. The optical scanner presented in this work consists of a laser diode, a scanning system and a signal detector. A 3D polymer gel dosimeter is measured in an immersion liquid in order to reduce deflection of the light from the dosimeter phantom. The very first results were obtained with the newly constructed scanner and PABIG^{nx} 3D polymer gel dosimeter, which was inhomogeneously irradiated with ^{192}Ir brachytherapy source. The results have been contrasted with those for the magnetic resonance imaging and are presented in this work together with the description of the developed instrument. Currently, the optimization of the optical scanner is performed.
Physical description
  • [1] J. Adamovics, M. Maryanski, Rad. Prot. Dosimetry 120, 107 (2006)
  • [2] J.C. Gore, Y.S. Kang, R.J. Schultz, Phys. Med. Biol. 29, 1189 (1984a)
  • [3] J.C. Gore, Y.S. Kang, R.J. Schultz, Magn. Reson. Imaging 2, 244 (1984b)
  • [4] L.E. Olsson, S. Petersson, L. Ahlgren, Phys. Med. Biol. 34, 43 (1989)
  • [5] R.J. Schulz, A.E. de Guzman, D.E. Nguten, J.C. Gore, Phys. Med. Biol. 35, 1611 (1990)
  • [6] T. Kron, P. Metealfe, J.M. Pope, Phys. Med. Biol. 38, 139 (1993)
  • [7] C. Duzenli, R. Sloboda, D. Robinson, Phys. Med. Biol. 39, 1577 (1994)
  • [8] G. Bartesaghi, M. Carrera, G. Gambarini, A. Negri, J. Phys.: Conf. Ser. 164, 012063 (2009)
  • [9] H. Fricke, S. Morse, Am. J. Roent. Rad. Ther. 18, 430 (1927)
  • [10] M.J. Maryanski, J.C. Gore, R.P. Kennan, R.J. Schulz, Magn. Reson. Imaging 11, 253 (1993)
  • [11] M.J. Maryanski, R.J. Schultz, G.S. Ibbott, J.C. Gatenby, J. Xie, D. Horton, J.C. Gore, Phys. Med. Biol. 39, 1437 (1994)
  • [12] M.J. Maryanski, G.S. Ibbott, P. Eastman, R.J. Schultz, J.C. Gore, Med. Phys. 23, 699 (1996)
  • [13] P.M. Fong, D.C. Keil, M.D. Does, J.C. Gore, Phys. Med. Biol. 46, 3105 (2001)
  • [14] Y. de Deene, C. Hurley, A.J. Venning, K. Vergote, M. Mather, B.J. Healy, C. Boldock, Phys. Med. Biol. 47, 3441 (2002)
  • [15] C. Hurley, A. Venning, C. Baldock, Appl. Radiat. Isot. 63, 443 (2005)
  • [16] A. Venning, B. Healy, K. Nitschke, C. Baldock, Nucl. Instrum. Methods Phys. Res. A 555, 396 (2005a)
  • [17] A. Venning, B. Hill, S. Brindha, B. Healy, C. Baldock, Phys. Med. Biol. 50, 3875 (2005b)
  • [18] E. Pappas, T. Maris, A. Angelopoulos, M. Paparigopoulou, L. Sakelliou, P. Sandilos, S. Voyiatzi, L. Vlachos, Phys. Med. Biol. 44, 2677 (1999)
  • [19] M. Kozicki, PhD thesis. Institute of Applied Radiation Chemistry, Technical University of Łódź, Poland 2004
  • [20] M. Kozicki, L. Petrokokkinos, P. Papagiannis, L. Sakelliou, A. Angelopoulos, E. Pappas, J.M. Rosiak, Biomed. Tech. 50, 1368 (2005)
  • [21] M. Kozicki, P. Maras, K. Rybka, T. Bieganski, S. Kadłubowski, L. Petrokokkinos, Macromol. Symp. 254, 345 (2007)
  • [22] E. Pantelis, C. Antypas, L. Petrokokkinos, P. Karaiskos, P. Papagiannis, M. Kozicki, E. Georgiou, L. Sakelliou, I. Seimenis, Med. Phys. 35, 2312 (2008)
  • [23] A. Moutsatsos, P. Karaiskos, L. Petrokokkinos, K. Zourari, E. Pantelis, L. Sakelliou, I. Seimenis, C. Constantinou, A. Peraticou, E. Georgiou, J. Phys.: Conf. Ser. 250, 012060 (2010)
  • [24] A.E. Papadakis, T.G. Maris, F. Zacharopoulou, E. Pappas, G. Zacharakis, J. Damilakis, Phys. Med. Biol. 52, 5069 (2007)
  • [25] K. Gut, D. Nabaglo, Acta Phys. Pol. A 116, 307 (2009)
  • [26] M. Kozicki, J.M. Rosiak, in: Proc. Second Int. Symp. on Reactive Polymers in Inhomogeneous Systems, in Melts and at Interfaces, Dresden (Germany), Book of abstract, 2003, S3/33
  • [27] M. Kozicki, Rad. Phys. Chem. 80, 1419 (2011)
Document Type
Publication order reference
YADDA identifier
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.