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2012 | 121 | 2 | 518-521
Article title

Nanocomposite Polymer Scaffolds for Bone Tissue Regeneration

Content
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Languages of publication
EN
Abstracts
EN
Nanocomposite polymer scaffolds for tissue engineering were prepared using leaching method. As a porogen there were used phosphate salts with different grain size (100-400 μm). Nanocomposite materials based on polylactide (PL/DLA) containing 2 wt% of ceramic bioactive nanoadditives (SiO_2) were prepared. The nanoadditive was characterized by dynamic light scatering (DLS) (size) and the Brunauer-Emmett-Teller (specific surface area) methods. Morphology of the nanoparticles was observed using the transmission electron microscopy. The optimal concentration of the nanofiller in the polymer matrix was evaluated on the basis of in vitro tests of the nanocomposite foils contacted with osteoblast-like human cells of MG63 line. The morphology and porosity of the scaffold after leaching was evaluated using scanning electron microscopy and hydrostatic weighing. The bioactivity test made on the scaffolds demonstrated ability to nucleation of apatite structure on the material.
Keywords
EN
Publisher

Year
Volume
121
Issue
2
Pages
518-521
Physical description
Dates
published
2012-02
Contributors
  • Faculty of Material Science and Ceramic, Department of Biomaterials, AGH-University of Science and Technology, Kraków, Poland
  • Faculty of Material Science and Ceramic, Department of Biomaterials, AGH-University of Science and Technology, Kraków, Poland
author
  • The Henryk Niewodniczański Institute of Nuclear Physics, Polish Academy of Sciences, Kraków, Poland
  • Faculty of Material Science and Ceramic, Department of Biomaterials, AGH-University of Science and Technology, Kraków, Poland
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-appv121n276kz
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