Fourier Transform Near Infrared Raman Spectroscopy in Studies on Connective Tissue

• Authors: M. Połomska , L. Kubisz , R. Kalawski , G. Oszkinis , R. Filipiak , A. Mazurek
• Languages of publication: EN

Abstracts

EN

Studies of tissue such as bones and veins often are carried out by means of microscopic and ultrasonographic methods. Therefore studies of changes caused by pathological or physical factors often are limited to morphological level. Application of Raman spectroscopy permits to associate morphological changes and molecular changes. The paper presents preliminary studies of temperature and ionizing radiation effects on Raman spectra of bone and collagen. Furthermore, effects of pathological factors on Raman spectra of human veins had been studied. It was noticed that heating of bone collagen up to 110°C gives the reversible changes in spectra. In the case of γ-irradiation, any effects were observed up to the dose of 1 MGy on mineral component of bone, whereas the influence on collagen was observed for doses higher than 100 kGy. The Raman spectra of varicose vs. normal veins permit to conclude some important changes observed for veins from chronic venous insufficiency patients.

Keywords

EN

78.30.-j; 78.30.Jw; 61.80.Ed; 61.82.Pv; 81.05.-t; 87.-g; 87.93.-j; 87.64.K-

Discipline

• 81.05.-t: Specific materials: fabrication, treatment, testing, and analysis(for superconducting materials, see 74.70.-b, and 74.72.-h; for magnetic materials, see 75.50.-y; for optical materials, see 42.70.-a; for dielectric materials, see 77.84.-s; for disperse systems and complex fluids, see 82.70.-y; see also 82.75.-z Molecular sieves, zeolites, clathrates, and other complex solids; for materials properties, see sections 60 and 70)
• 78.30.Jw: Organic compounds, polymers
• 87.64.K-: Spectroscopy
• 78.30.-j: Infrared and Raman spectra(for vibrational states in crystals and disordered systems, see 63.20.-e and 63.50.-x, respectively; for Raman spectra of superconductors, see 74.25.nd)
• 61.82.Pv: Polymers, organic compounds
• 61.80.Ed: γ-ray effects

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2010
• Volume: 118
• Issue: 1
• Pages: 136-140

Dates

published

2010-07

Contributors

author

M. Połomska

• Institute of Molecular Physics, Polish Academy of Sciences, M. Smoluchowskiego 17, 60 179 Poznań, Poland

author

L. Kubisz

• Department of Biophysics, Poznań University of Medical Sciences, Fredry 10, 61-701 Poznań, Poland

author

R. Kalawski

• Department of Cardiac Surgery, Municipal Hospital, Szkolna 8/12, 61-417 Poznań, Poland

author

G. Oszkinis

• Department of General and Vascular Surgery, Poznań University of Medical Sciences, Szkolna 8/12, Poznań, Poland

author

R. Filipiak

• Department of Cardiac Surgery, Municipal Hospital, Szkolna 8/12, 61-417 Poznań, Poland

author

A. Mazurek

• Department of Cardiac Surgery, Municipal Hospital, Szkolna 8/12, 61-417 Poznań, Poland

References

• 1. J.V. Psala, J. Melhuish, Br. J. Surg. 76, 37 (1989)
• 2. M.A. Elsharawy, M.M. Naim, E.M. Abdelmaguid, A.A. Al-Mulhim, Interactive Cardiovascular and Thoracic Surgery 6, 219 (2007)
• 3. C. Jeanneret, T. Baldi, S. Hailemariam, C. Koella, J. Gewaltig, B.C. Biedermann, Br. J. Surg. 94, 449 (2007)
• 4. B. Schrader, B. Dippel, I. Erb, S. Keller, T. Löchte, T. Schultz, E. Tatsch, S. Wessel, J. Mol. Struct. 480-481, 21 (1999)
• 5. B. Schrader, H. Schultz, G.N. Andreev, H.H. Klump, J. Sawatzki, Talanta 53, 35 (2000)
• 6. S. Fendel, B. Schrader, Fresenius J. Anal. Chem. 360, 609 (1998)
• 7. H.G.M. Edwards, D.W. Farwell, J.M. Holder, E.E. Lawson, J. Mol. Struct. 435, 49 (1997)
• 8. A. Carden, M.D. Morris, J. Biomed. Opt. 5, 259 (2000)
• 9. G. Frushour, J. Koenig, Biopolymers 14, 379 (1975)
• 10. J. Bandekar, Biochim. Biophys. Acta 1120, 123 (1992)
• 11. M. Sintzel, A. Merkli, C. Tabatabay, R. Gurny, Drug Development & Industrial Pharmacy 23, 9 (1997)
• 12. L. Kubisz, M. Połomska, Spectrochim. Acta A 66, 616 (2007)
• 13. S. Nomura, A. Hiltner, J.B. Lando, E. Baer, Biopolymers 16, 231 (1977)
• 14. L. Kubisz, S. Mielcarek, F. Jaroszyk, Int. J. Biol. Macromol. 33, 1 (2003)

Identifiers

DOI

10.12693/APhysPolA.118.136