Understanding Radiation Damage to Cells Using Microbeams

• Authors: M Folkard , K Prise , C Shao , S Gilchrist , G Schettino , A Michette , B Vojnovic
• Languages of publication: EN

Abstracts

EN

Cellular micro-irradiation techniques provide unique experimental opportunities for understanding how ionizing radiation interacts with living cells and tissues. Using microbeams, it is possible to deliver precise doses of radiation to selected individual cells, or sub-cellular targets in vitro. This technique continues to be applied to the investigation of a number of phenomena currently of great interest to the radiobiological community. In particular, it is the study of so-called "non-targeted" effects (where cells are seen to respond indirectly to ionizing radiation) that are benefiting most from the use of microbeam approaches.

Keywords

EN

41.75.Ak; 87.50.-a

Discipline

• 41.75.Ak: Positive-ion beams
• 87.50.-a: Effects of electromagnetic and acoustic fields on biological systems

• Journal: Acta Physica Polonica A
• Year: 2006
• Volume: 109
• Issue: 3
• Pages: 257-264

Dates

published

2006-03

received

2005-05-20

Contributors

author

M Folkard

• Gray Cancer Institute, Mount Vernon Hospital, P.O. Box 100, Northwood, HA6 2JR, UK

author

K Prise

• Gray Cancer Institute, Mount Vernon Hospital, P.O. Box 100, Northwood, HA6 2JR, UK

author

C Shao

• Gray Cancer Institute, Mount Vernon Hospital, P.O. Box 100, Northwood, HA6 2JR, UK

author

S Gilchrist

• Gray Cancer Institute, Mount Vernon Hospital, P.O. Box 100, Northwood, HA6 2JR, UK

author

G Schettino

• Gray Cancer Institute, Mount Vernon Hospital, P.O. Box 100, Northwood, HA6 2JR, UK

author

A Michette

• King's College London, Strand, London WC2R 2LS, UK

author

B Vojnovic

• Gray Cancer Institute, Mount Vernon Hospital, P.O. Box 100, Northwood, HA6 2JR, UK

References

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Identifiers

DOI

10.12693/APhysPolA.109.257