Qualification of the Most Statistically "Sensitive" Diffusion Tensor Imaging Parameters for Detection of Spinal Cord Injury

• Authors: A. Krzyżak , A. Jasiński , D. Adamek
• Languages of publication: EN

Abstracts

EN

Qualification of the most statistically "sensitive" diffusion parameters using Magnetic Resonance (MR) Diffusion Tensor Imaging (DTI) of the control and injured spinal cord of a rat in vivo and in vitro after the trauma is reported. Injury was induced in TH12/TH13 level by a controlled "weight-drop". In vitro experiments were performed in a home-built MR microscope, with a 6.4 T magnet, in vivo samples were measured in a 9.4 T/21 horizontal magnet The aim of this work was to find the most effective diffusion parameters which are useful in the statistically significant detection of spinal cord tissue damage. Apparent diffusion tensor (ADT) weighted data measured in vivo and in vitro on control and injured rat spinal cord (RSC) in the transverse planes and analysis of the diffusion anisotropy as a function of many parameters, which allows statisticall expose of the existence of the damage are reported.

Keywords

EN

01.30.-y; 87.57.-s; 07.57.Pt

Discipline

• 87.57.-s: Medical imaging
• 07.57.Pt: Submillimeter wave, microwave and radiowave spectrometers; magnetic resonance spectrometers, auxiliary equipment, and techniques
• 01.30.-y: Physics literature and publications

• Journal: Acta Physica Polonica A
• Year: 2005
• Volume: 108
• Issue: 1
• Pages: 207-210

Dates

published

2005-07

received

2005-04-24

Contributors

author

A. Krzyżak

• Department of Magnetic Resonance, H. Niewodniczaski Institute of Nuclear Physics, Kraków, Poland

author

A. Jasiński

• Department of Magnetic Resonance, H. Niewodniczaski Institute of Nuclear Physics, Kraków, Poland
• Department of Dielectrics and Biophysics, Pedagogical University, Kraków, Poland

author

D. Adamek

• Department of Neuropathology, Jagellonian University Medical College, Kraków, Poland

References

• 1. A.T. Krzyżak, A. Jasiński, D. Adamek, M. Baj, J. Kuśmiderski, P. Sagnowski, W.P. Węglarz, Proc. ISMRM VI Meeting, Sydney (1998) p. 1931.
• 2. U. Nevo, E. Hauben, E. Yoles, E. Agranov, S. Akselrod, M. Schwartz, M. Neeman, Magn. Res. Med. 45, 1 (2001).
• 3. P. Black, R.S. Markowitz, I. Damjanov, S.D. Finkelstein, H. Kushner, J. Gillespie, M. Feldman, Neurosurgery 22, 51 (1988).
• 4. A.T. Krzyżak, Ph.D. Thesis, Institute of Nuclear Physics, Kraków.

Identifiers

DOI

10.12693/APhysPolA.108.207