Magnetic Resonance Imaging Analysis of Moving Fronts in Floating Dosage Forms

• Authors: P. Kulinowski , P. Dorożyński , R. Jachowicz , A. Jasiński
• Languages of publication: EN

Abstracts

EN

An application of magnetic resonance imaging in the field of pharmaceutical technology is presented in this paper. The analysis of diffusion and swelling fronts was carried out for four floating dosage forms using magnetic resonance imaging. The influence of polymer viscosity, its concentration, and type of applied dissolution media on the area of moving fronts was investigated.

Keywords

EN

87.61.-c

Discipline

• 87.61.-c: Magnetic resonance imaging

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2005
• Volume: 108
• Issue: 1
• Pages: 155-160

Dates

published

2005-07

received

2005-04-24

Contributors

author

P. Kulinowski

• Department of Magnetic Resonance, Institute of Nuclear Physics PAS, Radzikowskiego 152, 31-342 Kraków, Poland

author

P. Dorożyński

• Department of Pharmaceutical Technology and Biopharmaceutics, Pharmaceutical Faculty, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

author

R. Jachowicz

• Department of Pharmaceutical Technology and Biopharmaceutics, Pharmaceutical Faculty, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

author

A. Jasiński

• Department of Magnetic Resonance, Institute of Nuclear Physics PAS, Radzikowskiego 152, 31-342 Kraków, Poland
• Pedagogical University, Podchorążych 2, 30-084 Kraków, Poland

References

• 1. P. Dorozyński, R. Jachowicz, P. Kulinowski, S. Kwieciński, K. Szybiński, T. Skórka, A. Jasiński, Drug Dev. Ind. Pharm., 30, 947, 2004
• 2. C.A. Fyfe, H. Grondey, A.I. Blazek-Welsh, S.K. Chopra, B.J. Fahie, J. Contr. Rel., 68, 73, 2000
• 3. D.G. Nishimura, A. Macovski, J.M. Pauly, IEEE Trans. Med. Imag., MI-5, 140, 1986
• 4. I.S. Moussa, L.H. Cartilier, J. Contr. Rel., 42, 47, 1996
• 5. N.A. Peppas, P. Bures, W. Leobandung, H. Ichikawa, Eur. J. Pharm. Biopharm., 50, 27, 2000

Identifiers

DOI

10.12693/APhysPolA.108.155