Modification of Polymer Substrates with Extreme Ultraviolet - Potential Application in Cancer Cell Identification

• Authors: I. Ahad , J. Pabijan , K. Pogoda , C. Hughes , A. Bartnik , H. Fiedorowicz , M. Lekka , D. Brabazon
• Languages of publication: EN

Abstracts

EN

During the last two decades, the development of laboratory scale extreme ultraviolet sources has been intensified due to growing interest in use of extreme ultraviolet photons for various applications in science and technology. In this study, we present a potential application of extreme ultraviolet sources for surface modification of polymers to be used as substrates for cancer cell identification. The surface modification of polytetrafluoroethylene (PTFE) polymer samples was performed by a lab scale compact laser-plasma extreme ultraviolet source based on a double-stream gas-puff target. The gas target was irradiated with a 3 ns/0.8 J Nd:YAG laser pulse at 10 Hz. Reference HCV29 non-malignant transitional epithelium and T24 bladder cancer cells adhesion and proliferation studies on pure and extreme ultraviolet sources modified PTFE surfaces were performed. The extreme ultraviolet modified surfaces demonstrated regular increase in cancer cell proliferation comparing to pristine sample. Initial results indicate that extreme ultraviolet treated substrates can facilitate the identification of cancer cells.

Keywords

EN

81.05.Lg; 81.40.Wx; 81.16.Rf; 81.65.-b

Discipline

• 81.05.Lg: Polymers and plastics; rubber; synthetic and natural fibers; organometallic and organic materials(for polymers and organic materials in electrochemistry, see 82.45.Wx)
• 81.16.Rf: Micro- and nanoscale pattern formation
• 81.40.Wx: Radiation treatment (particle and electromagnetic)(see also 61.80.-x Physical radiation effects, radiation damage)
• 81.65.-b: Surface treatments(for surface preparation and lithography in microelectronics, see 85.40.-e)

• Publisher: Institute of Physics, Polish Academy of Sciences
• Journal: Acta Physica Polonica A
• Year: 2018
• Volume: 133
• Issue: 2
• Pages: 283-285

Dates

published

2018-02

Contributors

author

I. Ahad

• Institute of Optoelectronics, Military University of Technology, 00-908 Warsaw, Poland
• Advanced Processing Technology Research Centre, School of Mechanical and Manufacturing Engineering, Faculty of Engineering and Computing, Dublin City University, Dublin 9, Ireland

author

J. Pabijan

• Institute of Nuclear Physics, Polish Academy of Sciences, E. Radzikowskiego 152, 31-342 Krakow, Poland

author

K. Pogoda

• Institute of Nuclear Physics, Polish Academy of Sciences, E. Radzikowskiego 152, 31-342 Krakow, Poland

author

C. Hughes

• Advanced Processing Technology Research Centre, School of Mechanical and Manufacturing Engineering, Faculty of Engineering and Computing, Dublin City University, Dublin 9, Ireland

author

A. Bartnik

• Institute of Optoelectronics, Military University of Technology, 00-908 Warsaw, Poland

author

H. Fiedorowicz

• Institute of Optoelectronics, Military University of Technology, 00-908 Warsaw, Poland

author

M. Lekka

• Institute of Nuclear Physics, Polish Academy of Sciences, E. Radzikowskiego 152, 31-342 Krakow, Poland

author

D. Brabazon

• Advanced Processing Technology Research Centre, School of Mechanical and Manufacturing Engineering, Faculty of Engineering and Computing, Dublin City University, Dublin 9, Ireland

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Identifiers

DOI

10.12693/APhysPolA.131.283