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2017 | 64 | 3 | 585-590
Article title

The effect of hydrazine derivatives of 3-formylchromones on angiogenic basic fibroblast growth factor and fibroblast growth factor receptor-1 in human melanoma cell line WM-115

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Languages of publication
EN
Abstracts
EN
The hydrazine derivatives of benzopyrones remain an unexplored group of chemical compounds. This preliminary study investigates the influence of A-5, CH-3 and K-2 derivatives at concentrations of 1, 10, 100 nM and 1 μM on selected biochemical factors of a melanoma cell line WM-115, with regard to their potential angiogenic properties. The studied compounds were found to influence cell proliferation, as well as total protein, bFGF and FGFR1 concentration.
Year
Volume
64
Issue
3
Pages
585-590
Physical description
Dates
published
2017
received
2017-03-14
revised
2017-07-11
accepted
2017-07-14
(unknown)
2017-09-07
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv64p585kz
Identifiers
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