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2017 | 64 | 1 | 21-24
Article title

Trypsin-specific Inhibitors from the Macrolepiota procera, Armillaria mellea and Amanita phalloides wild mushrooms

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EN
Abstracts
EN
Wild growing mushrooms are a rich source of novel proteins with unique features. We have isolated and characterized trypsin inhibitors from two edible mushrooms, the honey fungus (Armillaria mellea) and the parasol mushroom (Macrolepiota procera), and from the poisonous death cap (Amanita phalloides). The trypsin inhibitors isolated: armespin, macrospin and amphaspin, have similar molecular masses, acidic isoelectric points and are not N-glycosylated. They are very strong trypsin inhibitors and weak chymotrypsin inhibitors. They are resistant to exposure to high temperatures and withstand extreme pH values. These exceptional characteristics are advantageous for their potential use in biotechnology, agriculture and medicine.
Publisher

Year
Volume
64
Issue
1
Pages
21-24
Physical description
Dates
published
2017
received
2015-09-07
revised
2016-06-24
accepted
2016-06-26
(unknown)
2017-03-03
Contributors
author
  • Department of Biotechnology, Jožef Stefan Institute, SI1000 Ljubljana, Slovenia
author
  • Department of Biotechnology, Jožef Stefan Institute, SI1000 Ljubljana, Slovenia
author
  • Department of Biotechnology, Jožef Stefan Institute, SI1000 Ljubljana, Slovenia
  • Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, SI1000 Lubljana, Slovenia
  • Department of Biotechnology, Jožef Stefan Institute, SI1000 Ljubljana, Slovenia
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv64p21kz
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