Mechanisms of type I interferon action and its role in infections and diseases transmission in mammals

• Authors: Paulina Niedźwiedzka-Rystwej , Beata Tokarz-Deptuła , Wiesław Deptuła
• Languages of publication: EN

Abstracts

EN

Interferons (IFNs) are pivotal regulators of immunological processes. This paper describes mainly type I interferons -α and -β and their recently recounted signaling pathways, especially connected with ISGs - interferon stimulated genes, having a crucial role in regulating IFN recruitment. Moreover, the paper shows the data on the role of interferons -α and -β in infections - not only commonly known viral infections, but also bacterial, fungal and parasitic.

Keywords

EN

interferon; signaling pathway; infection; mammal

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2017
• Volume: 64
• Issue: 2
• Pages: 199-205

Dates

published

2017

received

2016-08-02

revised

2016-08-21

accepted

2016-08-21

(unknown)

2017-04-07

Contributors

author

Paulina Niedźwiedzka-Rystwej

• Department of Immunology, Faculty of Biology, University of Szczecin, Szczecin, Poland

author

Beata Tokarz-Deptuła

• Department of Immunology, Faculty of Biology, University of Szczecin, Szczecin, Poland

author

Wiesław Deptuła

• Department of Microbiology, Faculty of Biology, University of Szczecin, Szczecin, Poland

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Identifiers

DOI

10.18388/abp.2016_1403