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2017 | 64 | 1 | 117-122
Article title

The polar profile of ancient proteins: a computational extrapolation from prebiotics to paleobiochemistry

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Abstracts
EN
This paper addresses the polar profile of ancient proteins using a comparative study of amino acids found in 25 000 000-year-old shells described in Abelson's work. We simulated the polar profile with a computer platform that represented an evolutionary computational toy model that mimicked the generation of small proteins starting from a pool of monomeric amino acids and that included several dynamic properties, such as self-replication and fragmentation-recombination of the proteins. The simulations were taken up to 15 generations and produced a considerable number of proteins of 25 amino acids in length. The computational model included the amino acids found in the ancient shells, the thermal degradation factor, and the relative abundance of the amino acids observed in the Miller-Urey experimental simulation of the prebiotic amino acid formation. We found that the amino acid polar profiles of the ancient shells and those simulated and extrapolated from the Miller-Urey abundances are coincident.
Publisher

Year
Volume
64
Issue
1
Pages
117-122
Physical description
Dates
published
2017
received
2016-05-05
revised
2016-07-12
accepted
2016-10-30
(unknown)
2017-03-03
Contributors
  • Department of Mathematics, Faculty of Sciences, Universidad Nacional Autónoma de México, México City, 04510 México
author
  • Centro de Investigaciones Químicas, Universidad Autónoma del Estado de Morelos, Cuernavaca, Morelos, 62209 México
  • Department of Biochemistry, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", México City, 14000 México
  • Health Sciences Research Center, Faculty of Health Sciences, Universidad Anáhuac, Huixquilucan Edo. de México, 52786 México
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv64p117kz
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