Endothelial progenitor cells participation in cardiovascular and kidney diseases: a systematic review

• Authors: Jolanta Kiewisz , Monika Kaczmarek , Anna Pawlowska , Zbigniew Kmiec , Tomasz Stompor
• Languages of publication: EN

Abstracts

EN

Endothelial progenitor cells (EPCs) represent a small population of blood cells (5-40 cells/mm3), with an ability to differentiate into endothelial cells that form the lining of the blood vessels and contribute to postnatal angiogenesis. Abundant evidence shows that recruitment of EPCs from the bone marrow, the monocyte/macrophage lineage and the organs facilitate the endothelial regeneration and repair. Changes in the number of EPCs were observed in both, chronic kidney and cardiovascular diseases. Thus, these cells were tested for usage in diagnosis and therapy. In this paper, we review the current knowledge on the EPC biology and contribution of these cells to the kidney and cardiovascular diseases.

Keywords

EN

endothelial progenitor cells; chronic kidney diseases; cardiovascular diseases.

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2016
• Volume: 63
• Issue: 3
• Pages: 475-482

Dates

published

2016

received

2016-03-07

revised

2016-05-05

accepted

2016-05-18

(unknown)

2016-07-30

Contributors

author

Jolanta Kiewisz

• Faculty of Medical Sciences, Department of Human Histology and Embryology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

author

Monika Kaczmarek

• Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland

author

Anna Pawlowska

• Faculty of Medical Sciences Department of Nephrology, Hypertension and Internal Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

author

Zbigniew Kmiec

• Faculty of Medical Sciences, Department of Human Histology and Embryology, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

author

Tomasz Stompor

• Faculty of Medical Sciences Department of Nephrology, Hypertension and Internal Medicine, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland

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Identifiers

DOI

10.18388/abp.2016_1284