Daptomycin-resistant Staphylococcus pettenkoferi of human origin

• Authors: Vincenzo Savini , Maja Kosecka , Ed Siegwart , Roberta Marrollo , Ennio Polilli , Dalia Palmieri , Paolo Fazii , Edoardo Carretto , Jacek Międzobrodzki , Michal Bukowski
• Languages of publication: EN

Abstracts

EN

The importance of nosocomial infections caused by coagulase-negative staphylococci is constantly growing. The threat primarily affects immunocompromised patients, the elderly and neonates, particularly after invasive surgery. The problem is fundamentally exacerbated by expanding antibacterial drug resistance. A case report is presented of an 86-year-old patient who underwent a ruptured abdominal aortic aneurysm surgery and developed septicaemia upon surgical wound infection. The causal agent was likely a carbapenem-resistant Klebsiella pneumoniae, however, daptomycin-resistant Staphylococcus pettenkoferi was identified in blood cultures in the absence of daptomycin treatment. To the authors' knowledge, the case study presented is the first published episode of daptomycin-resistant S. pettenkoferi strain.

Keywords

EN

daptomycin resistance; coagulase-negative staphylococci; Staphylococcus pettenkoferi; Klebsiella pneumoniae

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2016
• Volume: 63
• Issue: 2
• Pages: 297-301

Dates

published

2016

received

2015-07-30

revised

2015-10-23

accepted

2015-12-16

(unknown)

2016-01-07

Contributors

author

Vincenzo Savini

• Clinical Microbiology and Virology, Spirito Santo Hospital, Pescara, Italy

author

Maja Kosecka

• Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland

author

Ed Siegwart

• LGC Ltd, Newmarket Rd, Fordham, Cambridgeshire, United Kingdom

author

Roberta Marrollo

• Clinical Microbiology and Virology, Spirito Santo Hospital, Pescara, Italy

author

Ennio Polilli

• Clinical Microbiology and Virology, Spirito Santo Hospital, Pescara, Italy

author

Dalia Palmieri

• Epidemiological Office, Spirito Santo Hospital, Pescara, Italy

author

Paolo Fazii

• Clinical Microbiology and Virology, Spirito Santo Hospital, Pescara, Italy

author

Edoardo Carretto

• Laboratory of Microbiology, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy

author

Jacek Międzobrodzki

• Department of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland

author

Michal Bukowski

• Department of Analytical Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland

References

• Bayer AS, Mishra NN, Chen L, Kreiswirth BN, Rubio A, Yang SJ (2015) Frequency and distribution of single nucleotide polymorphisms within mprF in methicillin-resistant Staphylococcus aureus (MRSA) Clinical Isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides. Antimicrob Agents Chemother 59: 4930-4937. doi: 10.1128/AAC.00970-15.
• Becker K, Harmsen D, Mellmann A, Meier C, Schumann P, Peters G, von Eiff C (2004) Development and evaluation of a quality-controlled ribosomal sequence database for 16S ribosomal DNA-based identification of Staphylococcus species. J Clin Microbiol 42: 4988-4995.
• Bukowski M, Polakowska K, Ilczyszyn WM, Sitarska A, Nytko K, Kosecka M, Miedzobrodzki J, Dubin A, Wladyka B (2015) Species determination within Staphylococcus genus by extended PCR-restriction fragment length polymorphism of saoC gene. FEMS Microbiol Lett 362: 1-11. doi: 10.1093/femsle/fnu007.
• Cockerill FR, Wikler MA, Alder J, Dudley MN, Eliopoulos GM, Ferraro MJ, Hardy DJ, Hecht DW, Hindler JA, Patel JB, Powell M, Swenson JM, Jr. RBT, Traczewski MM, Turnidge JD, Weinstein MP, Zimmer BL (2013) Performance standards for antimicrobial susceptibility testing; twenty-second informational supplement, Clinical and Laboratory Standards Institute.
• Cockerill FR, Wikler MA, Alder J, Dudley MN, Eliopoulos GM, Ferraro MJ, Hardy DJ, Hecht DW, Hindler JA, Patel JB, Powell M, Swenson JM, Richard B. Thomson J, Traczewski MM, Turnidge JD, Weinstein MP, Zimmer BL (2012) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standards 9th edn, Clinical and Laboratory Standards Institute.
• Davies J, Davies D (2010) Origins and evolution of antibiotic resistance. Microbiol Mol Biol Rev 74: 417-433. doi: 10.1128/MMBR.00016-10.
• Drancourt M, Raoult D (2002) rpoB gene sequence-based identification of Staphylococcus species. J Clin Microbiol 40: 1333-1338.
• Dubois D, Leyssene D, Chacornac JP, Kostrzewa M, Schmit PO, Talon R, Bonnet R, Delmas J (2010) Identification of a variety of Staphylococcus species by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J Clin Microbiol 48: 941-945. doi: 10.1128/JCM.00413-09.
• D'Azevedo PA, Siquiera I, Gugel J, Antunes AL, Secchi C, Pasternak J, Martino MD (2009) Evaluation of the automated system Vitek2 for identification and antimicrobial susceptibility testing of Brazilian Gram-positive cocci strains. Braz J Infect Dis 13: 107-110.
• Fluit AC, Carpaij N, Majoor EA, Bonten MJ, Willems RJ (2013) Shared reservoir of ccrB gene sequences between coagulase-negative staphylococci and methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother 68: 1707-1713. doi: 10.1093/jac/dkt121.
• Haigh JD, Green IM, Ball D, Eydmann M1, Millar M1, Wilks M (2013) Rapid identification of bacteria from bioMérieux BacT/ALERT blood culture bottles by MALDI-TOF MS. Br J Biomed Sci 70: 149-155.
• Krediet TG, Mascini EM, van Rooij E, Vlooswijk J, Paauw A, Gerards LJ, Fleer A (2004) Molecular epidemiology of coagulase-negative staphylococci causing sepsis in a neonatal intensive care unit over an 11-year period. J Clin Microbiol 42: 992-995.
• Loïez C, Wallet F, Pischedda P, Renaux E, Senneville E, Mehdi N, Courcol RJ (2007) First case of osteomyelitis caused by Staphylococcus pettenkoferi. J Clin Microbiol 45: 1069-1071.
• Mammina C, Bonura C, Verde MS, Fasciana T, Palma DM (2011) A fatal bloodstream infection by Staphylococcus pettenkoferi in an intensive care unit patient. Case Rep Crit Care 2011: 612732. doi: 10.1155/2011/612732.
• Mihaila L, Defrance G, Levesque E, Ichai P, Garnier F, Derouin V, Decousser JW, Doucet-Populaire F, Bourgeois-Nicolaos N (2012) A dual outbreak of bloodstream infections with linezolid-resistant Staphylococcus epidermidis and Staphylococcus pettenkoferi in a liver Intensive Care Unit. Int J Antimicrob Agents 40: 472-474. doi: 10.1016/j.ijantimicag.2012.06.014.
• Mkrtchyan H V, Russell CA, Wang N, Cutler RR (2013) Could public restrooms be an environment for bacterial resistomes? PloS One 8: e54223. doi: 10.1371/journal.pone.0054223.
• Morfin-Otero R, Martínez-Vázquez MA, López D, Rodríguez-Noriega E, Garza-González E (2012) Isolation of rare coagulase-negative isolates in immunocompromised patients: Staphylococcus gallinarum, Staphylococcus pettenkoferi and Staphylococcus pasteuri. Ann Clin Lab Sci 42: 182-185.
• Park S, Chung HS, Lee M (2015) Clinical and microbiological characteristics of six Staphylococcus pettenkoferi isolates from blood samples. Ann Lab Med 35: 250-253. doi: 10.3343/alm.2015.35.2.250.
• Rasigade JP, Raulin O, Picaud JC, Tellini C, Bes M, Grando J, Ben Saïd M, Claris O, Etienne J, Tigaud S, Laurent F (2012) Methicillin-resistant Staphylococcus capitis with reduced vancomycin susceptibility causes late-onset sepsis in intensive care neonates. PLoS One 7: e31548. doi: 10.1371/journal.pone.0031548.
• Rasigade JP, Vandenesch F (2014) Staphylococcus aureus: A pathogen with still unresolved issues. Infect Genet Evol 21: 510-514. doi: 10.1016/j.meegid.2013.08.018.
• Sa A, Yugueros J, Temprano A, Luengo A, Animal DD, Sánchez M, Luengo JM, Naharro G (2001) Identification of Staphylococcus spp. by PCR-restriction fragment length polymorphism of gap gene. J Clin Microbiol 39: 3693-3695.
• Seng P, Drancourt M, Gouriet F, La Scola B, Fournier PE, Rolain JM, Raoult D (2009) Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin Infect Dis 49: 543-551. doi: 10.1086/600885.
• Song SH, Park JS, Kwon HR, Kim SH, Kim HB, Chang HE, Park KU, Song J, Kim EC (2009) Human bloodstream infection caused by Staphylococcus pettenkoferi. J Med Microbiol 58: 270-272. doi: 10.1099/jmm.0.004697-0.
• Tótoli EG, Garg S, Salgado HR (2015) Daptomycin: Physicochemical, analytical, and pharmacological properties. Ther Drug Monit 37: 699-710.
• Trülzsch K, Grabein B, Schumann P, Mellmann A, Antonenka U, Heesemann J, Becker K (2007) Staphylococcus pettenkoferi sp. nov., a novel coagulase-negative staphylococcal species isolated from human clinical specimens. Int J Syst Evol Microbiol 57: 1543-1548.
• Trülzsch K, Rinder H, Trcek J, Bader L, Wilhelm U, Heesemann J (2002) Staphylococcus pettenkoferi a novel staphylococcal species isolated from clinical specimens. Diagn Microbiol Infect Dis 43: 175-182.
• Wójkowska-Mach J, Gulczyńska E, Nowiczewski M, Borszewska-Kornacka M, Domańska J, Merritt TA, Helwich E, Kordek A, Pawlik D, Gadzinowski J, Szczapa J, Adamski P, Sulik M, Klamka J, Brzychczy-Włoch M, Heczko PB (2014) Late-onset bloodstream infections of very-low-birth-weight infants: data from the Polish Neonatology Surveillance Network in 2009-2011. BMC Infect Dis 14: 339. doi: 10.1186/1471-2334-14-339.
• Yamaguchi T, Suzuki S, Okamura S, Miura Y, Tsukimori A, Nakamura I, Ito N, Masuya A, Shiina T, Matsumoto T (2015) Evolution and single-nucleotide polymorphisms in methicillin-resistant Staphylococcus aureus strains with reduced susceptibility to vancomycin and daptomycin, based on determination of the complete genome. Antimicrob Agents Chemother 59: 3585-3587. doi: 10.1128/AAC.05159-14.
• Yang SJ, Mishra NN, Rubio A, Bayer AS (2013) Causal role of single nucleotide polymorphisms within the mprF gene of Staphylococcus aureus in daptomycin resistance. Antimicrob Agents Chemother 57: 5658-5664. doi: 10.1128/AAC.01184-13.
• Young BC, Golubchik T, Batty EM, Fung R, Larner-Svensson H, Votintseva AA, Miller RR, Godwin H, Knox K, Everitt RG, Iqbal Z, Rimmer AJ, Cule M, Ip CL, Didelot X, Harding RM, Donnelly P, Peto TE, Crook DW et al. (2012) Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease. Proc Natl Acad Sci USA 109: 4550-4555. doi: 10.1073/pnas.1113219109.
• Yugueros J, Temprano A, Berzal B, Sánchez M, Hernanz C, Luengo JM, Naharro G (2000) Glyceraldehyde-3-phosphate dehydrogenase-encoding gene as a useful taxonomic tool for Staphylococcus spp. J Clin Microbiol 38: 4351-4355.

Identifiers

DOI

10.18388/abp.2015_1113