Influence of silver nanoparticles on metabolism and toxicity of moulds

• Authors: Katarzyna Pietrzak , Magdalena Twarużek , Agata Czyżowska , Robert Kosicki , Beata Gutarowska
• Languages of publication: EN

Abstracts

EN

The unique antimicrobial features of silver nanoparticles (AgNPs) are commonly applied in innumerable products. The lack of published studies on the mechanisms of AgNPs action on fungi resulted in identification of the aim of this study, which was: the determination of the influence of AgNPs on the mould cytotoxicity for swine kidney cells (MTT test) and the production of selected mycotoxins, organic acids, extracellular enzymes by moulds. The conducted study had shown that silver nanoparticles can change the metabolism and toxicity of moulds. AgNPs decrease the mycotoxin production of Aspergillus sp. (81-96%) and reduce mould cytotoxicity (50-75%). AgNPs influence the organic acid production of A. niger and P. chrysogenum by decreasing their concentration (especially of the oxalic and citric acid). Also, a change in the extracellular enzyme profile of A. niger and P. chrysogenum was observed, however, the total enzymatic activity was increased.

Keywords

EN

silver nanoparticles; moulds; mycotoxins; cytotoxicity; MTT; organic acids; extracellular enzymes

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2015
• Volume: 62
• Issue: 4
• Pages: 851-857

Dates

published

2015

received

2015-08-01

revised

2015-10-01

accepted

2015-10-30

(unknown)

2015-12-04

Contributors

author

Katarzyna Pietrzak

• Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Łódź, Poland

author

Magdalena Twarużek

• Institute of Experimental Biology, Kazimierz Wielki University, Bydgoszcz, Poland

author

Agata Czyżowska

• Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Łódź, Poland

author

Robert Kosicki

• Institute of Experimental Biology, Kazimierz Wielki University, Bydgoszcz, Poland

author

Beata Gutarowska

• Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Łódź, Poland

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Identifiers

DOI

10.18388/abp.2015_1146