Response of vitamins A, E, hematological and serum biochemical markers in Crucian carp (Carassius auratus gibelio) exposed to environmental Pb2+ and Cd2+

• Authors: Sher Khan , Peiyuan Zhou , Xiaoyu Liu , Hong Li , Jingna Li , Zia ur Rehman , Ijaz Ahmad
• Languages of publication: EN

Abstracts

EN

Toxicity of Pb2+ and Cd2+ is a widespread issue in the world; however, few studies have been conducted to understand their effect at environmentally realistic concentration in a mixture. In the present study, Crucian carp was exposed to Pb2+ (30 µg·l-1), Cd2+ (100 µg·l-1) and their mixture (30+100 µg·l-1) for 96 h and 21 d period to assess changes in the liver and muscle vitamin A and E content, and hematological and serum biochemical parameters. The results indicated significant decline in the level of antioxidant vitamins A, E and alterations in the hematological and serum biochemical indices. The toxicity revealed anemia, impairment of the liver and kidney with evident responses after 21 d exposure due to additive effect of Pb2+ and Cd2+ in mixture. Moreover, the differential response of vitamins A, E and blood parameters to low levels of waterborne Pb2+ and Cd2+ in freshwater fish can be used as biomarkers for monitoring contamination of aquatic environment.

Keywords

EN

vitamins A and E; hematology; serum chemistry; Crucian carp (Carassius auratus gibelio); Cd2+; Pb2+

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2015
• Volume: 62
• Issue: 3
• Pages: 581-587

Dates

published

2015

received

2015-04-23

revised

2015-07-27

accepted

2015-07-31

(unknown)

2015-09-03

Contributors

author

Sher Khan

• College of Food Science & Technology, Huazhong Agricultural University Wuhan, 430070, P. R. China

author

Peiyuan Zhou

• College of Food Science & Technology, Huazhong Agricultural University Wuhan, 430070, P. R. China

author

Xiaoyu Liu

• College of Food Science & Technology, Huazhong Agricultural University Wuhan, 430070, P. R. China
• Key Laboratory of Environment Correlative Dietology, Ministry of Education Wuhan, 430070, P. R. China

author

Hong Li

• College of Food Science & Technology, Huazhong Agricultural University Wuhan, 430070, P. R. China

author

Jingna Li

• College of Food Science & Technology, Huazhong Agricultural University Wuhan, 430070, P. R. China

author

Zia ur Rehman

• Key Laboratory of Animal Genetics, Breeding and Reproduction, Huazhong Agricultural University Wuhan, 430070, P. R. China

author

Ijaz Ahmad

• National Reference Laboratory of Veterinary Drug Residues (HZAU) and MAO Key Laboratory for Detection of Veterinary Drug Residues, Huazhong Agricultural University Wuhan, 430070, P. R. China

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Identifiers

DOI

10.18388/abp.2015_1036