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2014 | 61 | 4 | 727-729
Article title

Differentiation by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) of Candida albicans isolated from upper respiratory tract in patients with non-small cell lung cancer

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EN
Abstracts
EN
Cancer patients are predisposed to fungal infections caused by Candida albicans, especially to oral or respiratory tract candidiasis. The aim of this study was to estimate genetic diversity by RAPD-PCR (random amplified polymorphic DNA-polymerase chain reaction) of C. albicans isolated from upper respiratory tract of 100 patients with non-small cell lung cancer. Among 52 strains, 34 genotypes were defined. 10 clusters comprising 28 (53.85%) isolates with similarity coefficient ≥ 80% were formed. The remaining 24 (46.15%) isolates represented individual genotypes. The RAPD-PCR technique revealed genomic variability within C. albicans isolated from upper respiratory tract of the cancer patients.
Publisher

Year
Volume
61
Issue
4
Pages
727-729
Physical description
Dates
published
2014
received
2013-11-29
revised
2014-06-12
accepted
2014-10-17
(unknown)
2014-11-06
Contributors
  • Department of Pharmaceutical Microbiology, Medical University of Lublin, Lublin, Poland
  • Department of Pharmaceutical Microbiology, Medical University of Lublin, Lublin, Poland
  • Department of Pharmaceutical Microbiology, Medical University of Lublin, Lublin, Poland
author
  • Department of Pharmaceutical Microbiology, Medical University of Lublin, Lublin, Poland
References
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Document Type
Publication order reference
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YADDA identifier
bwmeta1.element.bwnjournal-article-abpv61p727kz
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