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2014 | 61 | 4 | 663-669
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The rules of aging: are they universal? Is the yeast model relevant for gerontology?

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The success of experimental biology was possible due to the use of model organisms. It is believed that the mechanisms of aging have a universal character and they are conserved in a wide range of organisms. The explanation of these universal mechanisms by tracing survival curves of model organisms clearly suggests that death of individuals is a direct consequence of aging. Furthermore, the use of unicellular organisms like yeast Saccharomyces cerevisiae to explain the aging processes of multicellular organisms runs the risk of oversimplification. Aging is a very complex process and therefore in this paper we present arguments suggesting that some of these fundamental assumptions require a deep rethinking and verification.
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  • Department of Biochemistry and Cell Biology, University of Rzeszow, Rzeszów, Poland
  • Department of Biochemistry and Cell Biology, University of Rzeszow, Rzeszów, Poland
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