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2014 | 61 | 3 | 441-451
Article title

Mapping of the influenza A hemagglutinin serotypes evolution by the ISSCOR method

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Analyses and visualizations by the ISSCOR method of influenza virus hemagglutinin genes of different A-subtypes revealed some rather striking temporal relationships between groups of individual gene subsets. Based on these findings we consider application of the ISSCOR-PCA method for analyses of large sets of homologous genes to be a worthwhile addition to a toolbox of genomics - allowing for a rapid diagnostics of trends, and ultimately even aiding an early warning of newly emerging epidemiological threats.

Physical description
  • Interdisciplinary Center for Mathematical and Computational Modeling, Warsaw University, Warsaw, Poland
  • Centre de Génétique Moléculaire du CNRS & Université Pierre-et-Marie Curie, Paris, Gif sur Yvette, France
  • Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland
  • Institute of Biotechnology and Antibiotics, Warsaw, Poland
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