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2014 | 61 | 1 | 123-127
Article title

The effect of Galleria mellonella hemolymph polypeptides on Legionella gormanii

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EN
Abstracts
EN
Among Legionella species, which are recognized to be pathogenic for humans, L. gormanii is the second prevalent causative agent of community-acquired pneumonia after L. pneumophila. Anti-L. gormanii activity of Galleria mellonella hemolymph extract and apolipophorin III (apoLp-III) was examined. The extract and apoLp-III at the concentration 0.025 mg/ml caused 75% and 10% decrease of the bacteria survival rate, respectively. The apoLp-III-induced changes of the bacteria cell surface were analyzed for the first time by atomic force microscopy. Our studies demonstrated the powerful anti-Legionella effects of the insect defence polypeptides, which could be exploited in drugs design against these pathogens.
Year
Volume
61
Issue
1
Pages
123-127
Physical description
Dates
published
2014
received
2013-10-28
revised
2014-02-22
accepted
2014-02-25
(unknown)
2014-03-20
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv61p123kz
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