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2013 | 60 | 4 | 871-873
Article title

Prp4 kinase is required for proper segregation of chromosomes during meiosis in Schizosaccharomyces pombe

Content
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EN
Abstracts
EN
Chromosome segregation during meiosis is a complex process, which leads to production of four haploid gametes from two precursor cells. Reversible phosphorylation of proteins plays a crucial role in this process. The Schizosaccharomyces pombe Prp4 is an essential serine/threonine protein kinase, which belongs to the Clk/Sty family. To study the role of Prp4 in meiosis, we analysed chromosome segregation in a strain carrying conditional analog-sensitive allele of Prp4 protein kinase (prp4-as2). Our data show, that Prp4 protein kinase plays important role in chromosome segregation during meiosis, as revealed by enhanced missegregation of chromosomes in prp4-as2 mutant cells.
Year
Volume
60
Issue
4
Pages
871-873
Physical description
Dates
published
2013
received
2013-10-15
revised
2013-12-03
accepted
2013-12-18
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv60p871kz
Identifiers
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