Carotenoid composition and in vitro pharmacological activity of rose hips

• Authors: Györgyi Horváth , Péter Molnár , Erika Radó-Turcsi , József Deli , Masami Kawase , Kazue Satoh , Toru Tanaka , Satoru Tani , Hiroshi Sakagami , Nóra Gyémánt , József Molnár
• Languages of publication: EN

Abstracts

EN

The aim of the present study was to compare carotenoid extracts of Rose hips (Rosa canina L.) with regard to their phytochemical profiles and their in vitro anti-Helicobacter pylori (H. pylori), cytotoxic, multidrug resistance (MDR) reversal and radical scavenging activity. Carotenoid composition was investigated in the different fractionation of rose hips, using extraction methods. Six main carotenoids - epimers of neochrome, lutein, zeaxanthin, rubixanthin, lycopene, β,β-carotene - were identified from Rose hips by their chromatographic behavior and UV-visible spectra, which is in accordance with other studies on carotenoids in this plant material. The active principles in the carotenoid extract might differ, depending upon the extraction procedures.

Keywords

EN

radical intensity; cytotoxic activity; carotenoids; Rosa canina L.; MDR; anti-H. pylori

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2012
• Volume: 59
• Issue: 1
• Pages: 129-132

Dates

published

2012

received

2011-10-14

accepted

2012-03-01

(unknown)

2012-03-17

Contributors

author

Györgyi Horváth

• Department of Pharmacognosy, University of Pécs, Medical School, Pécs, Hungary

author

Péter Molnár

• Department of Pharmacognosy, University of Pécs, Medical School, Pécs, Hungary

author

Erika Radó-Turcsi

• Department of Biochemistry and Medical Chemistry, University of Pécs, Pécs, Hungary

author

József Deli

• Department of Biochemistry and Medical Chemistry, University of Pécs, Pécs, Hungary

author

Masami Kawase

• Faculty of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime, Japan

author

Kazue Satoh

• School of Medicine, Showa University, Shinagawa, Tokyo, Japan

author

Toru Tanaka

• Faculty of Pharmaceutical Sciences, Josai University, Sakado, Saitama, Japan

author

Satoru Tani

• Faculty of Pharmaceutical Sciences, Josai University, Sakado, Saitama, Japan

author

Hiroshi Sakagami

• Division of Pharmacology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry, Sakado, Saitama, Japan

author

Nóra Gyémánt

• Faculty of Medicine, Institute of Medical Microbiology, Albert Szent-Györgyi Medical Centrum, University of Szeged, Szeged, Hungary

author

József Molnár

• Faculty of Medicine, Institute of Medical Microbiology, Albert Szent-Györgyi Medical Centrum, University of Szeged, Szeged, Hungary

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