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2010 | 57 | 1 | 75-82
Article title

New method for the study of Amaryllidaceae alkaloid biosynthesis using biotransformation of deuterium-labeled precursor in tissue cultures

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EN
Abstracts
EN
Biotransformation of deuterated-4'-O-methylnorbelladine into alkaloids galanthamine and lycorine in tissue cultures of Leucojum aestivum was demonstrated using HPLC coupled to mass spectrometry. GC-MS screening was also carried to investigate other native and deuterated alkaloids. A total of six labeled alkaloids were identified indicating that 4'-O-methyl-d3-norbelladine is incorporated into three different groups of Amaryllidaceae alkaloids that are biosynthesized by three modes of intramolecular oxidative phenol coupling.
Year
Volume
57
Issue
1
Pages
75-82
Physical description
Dates
published
2010
received
2009-10-15
revised
2009-12-05
accepted
2009-12-15
(unknown)
2010-01-11
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.bwnjournal-article-abpv57p75kz
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