Pain and mobility improvement and MDA plasma levels in degenerative osteoarthritis, low back pain, and rheumatoid arthritis after infrared A-irradiation

• Authors: Werner Siems , Nikolaus Bresgen , Rainer Brenke , Renate Siems , Manfred Kitzing , Heike Harting , Peter M Eckl
• Languages of publication: EN

Abstracts

EN

Infrared (IR)-A irradiation can be useful in back and musculoskeletal pain therapy. In this study joint and vertebral column pain and mobility were measured during two weeks of IR-A irradiation treatment of patients suffering from degenerative osteoarthritis of hip and knee, low back pain, or rheumatoid arthritis. Additionally, before and after IR-A treatment MDA serum levels were measured to check if MDA variations accompany changes in pain intensity and mobility. Two-hundred and seven patients were divided into verum groups getting IR-irradiation, placebo groups getting visible, but not IR irradiation, and groups getting no irradiation. In osteoarthritis significant pain reduction according to Visual Analogue Scale and mobility improvements occurred in the verum group. Even though beneficial mean value changes occurred in the placebo group, the improvements in the placebo and No Irradiation groups were without statistical significance. In low back pain, pain and mobility improvements (by 35-40%) in the verum group were found, too. A delayed (2nd week) mobility improvement in rheumatoid arthritis was seen. However, pain relief was seen immediately. In patients suffering from low back pain or rheumatoid arthritis, the pain and mobility improvements were accompanied by significant changes of MDA serum levels. However, MDA appears not a sensitive biofactor for changes of the pain intensity in degenerative osteoarthritis. Nevertheless, unaffected or lowered MDA levels during intensive IR-A therapy argue against previous reports on free radical formation upon infrared. In conclusion, rapid beneficial effects of IR-A towards musculoskeletal pain and joint mobility loss were demonstrated.

Keywords

EN

rheumatoid arthritis; infrared; malondialdehyde (MDA); lipid peroxidation; pain; osteoarthritis

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2010
• Volume: 57
• Issue: 3
• Pages: 313-319

Dates

published

2010

received

2009-12-11

revised

2010-06-26

accepted

2010-08-16

(unknown)

2010-09-08

Contributors

author

Werner Siems

• KortexMed Bad Harzburg, Research Institute of Physiotherapy and Gerontology, Bad Harzburg, Germany

author

Nikolaus Bresgen

• University of Salzburg, Department of Cell Biology, Salzburg, Austria

author

Rainer Brenke

• Hufeland-Hospital, Center for Pneumology, Allergology, Natural Medicine and Orthopaedics, Bad Ems, Germany

author

Renate Siems

• KortexMed Bad Harzburg, Research Institute of Physiotherapy and Gerontology, Bad Harzburg, Germany

author

Manfred Kitzing

• KortexMed Bad Harzburg, Research Institute of Physiotherapy and Gerontology, Bad Harzburg, Germany

author

Heike Harting

• KortexMed Bad Harzburg, Research Institute of Physiotherapy and Gerontology, Bad Harzburg, Germany

author

Peter M Eckl

• University of Salzburg, Department of Cell Biology, Salzburg, Austria

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