New cationic polyprenyl derivative proposed as a lipofecting agent

• Authors: Zbigniew Madeja , Monika Rak , Ewa Wybieralska , Igor Różański , Marek Masnyk , Marek Chmielewski , Robert Łysek , Tadeusz Chojnacki , Wiesław Jankowski , Ewa Ciepichal , Ewa Swiezewska , Michael Tekle , Gustav Dallner
• Languages of publication: EN

Abstracts

EN

Cationic linear poly-cis-isoprenoid prepared from natural plant polyprenol in a mixture with dioleyl phosphatidylethanolamine was found to be an effective lipofection agent for eukaryotic cells. The transfecting activity is related to the poly-cis structure of the polyprenyl chain.

Keywords

EN

lipofection; transfection; GFP; cationic polyprenyl

• Publisher: Polish Biochemical Society
• Journal: Acta Biochimica Polonica
• Year: 2007
• Volume: 54
• Issue: 4
• Pages: 873-876

Dates

published

2007

received

2007-08-24

revised

2007-09-19

accepted

2007-09-22

(unknown)

2007-12-08

Contributors

author

Zbigniew Madeja

• Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

author

Monika Rak

• Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

author

Ewa Wybieralska

• Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

author

Igor Różański

• Department of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland

author

Marek Masnyk

• Institute of Organic Chemistry PAS, Warszawa, Poland

author

Marek Chmielewski

• Institute of Organic Chemistry PAS, Warszawa, Poland

author

Robert Łysek

• Institute of Organic Chemistry PAS, Warszawa, Poland

author

Tadeusz Chojnacki

• Institute of Biochemistry and Biophysics PAS, Warszawa, Poland

author

Wiesław Jankowski

• Institute of Biochemistry and Biophysics PAS, Warszawa, Poland

author

Ewa Ciepichal

• Institute of Biochemistry and Biophysics PAS, Warszawa, Poland

author

Ewa Swiezewska

• Institute of Biochemistry and Biophysics PAS, Warszawa, Poland

author

Michael Tekle

• Arrhenius Laboratory, Department of Biochemistry and Biophysics, Stockholm University

author

Gustav Dallner

• Arrhenius Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden

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