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Number of results
2007 | 54 | 4 | 853-856

Article title

Analysis of gypsogenin saponins in homeopathic tinctures

Content

Title variants

Languages of publication

EN

Abstracts

EN
A relatively simple and short procedure for the quantitative determination of gypsogenin saponins was performed to evaluate homeopathic tinctures in which those compounds can be regarded as one of the active constituents. This method comprises partial hydrolysis of saponins, subsequent extraction of liberated prosaponin (gypsogenin 3-O-glucuronide) and its analysis by high performance liquid chromatography. Glycyrrhizic acid was used as an internal standard. This method was successfully applied to the analysis of mother tinctures obtained from Saponaria officinalis. Thus, the determination of triterpenoid saponins can be used as a convenient and sufficient method of standardization of selected homeopathic tinctures.

Year

Volume

54

Issue

4

Pages

853-856

Physical description

Dates

published
2007
received
2007-07-24
revised
2007-09-26
accepted
2007-11-07
(unknown)
2007-12-09

Contributors

author
  • Department of Plant Biochemistry, Institute of Biochemistry, University of Warsaw, Warszawa, Poland
author
  • Laboratoire de Botanique et Mycologie, Faculté de Pharmacie, Université Henri Poincaré, Nancy cedex, France

References

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  • Directive 2001/83/EC and 2004/27/EC of the European Parliament and of the Council on the Community code relating to medicinal products for human use.
  • EMEA/HMPWG/25/99, EMEA/CPMP/ICH/281/95, http://www.eudra.org.emea.html
  • Eudra/Q/92/021: 'Note for Guidance on stability testing of new active substances and medicinal products'.
  • Frye J C (2003) Seminars in Integrative Medicine 1: 158-166.
  • Henry M, Pauthe-Dayde D, Rochd M (1989) J Chromatogr 477: 413-415.
  • Lyakina MN (2004) Pharm Chem J 38: 28-30.
  • Nandi M (1999) Br Homeopath J 88: 161-165.
  • Oleszek WA (2002) J Chromatogr A 967: 147-162.
  • Selivantchikova IB, Lyakina MN, Kostennikova ZP (2001) Farmatsija 6: 14-15.
  • Satti J (2005) Seminars in Integrative Medicine 3: 113-122.
  • Sparg SG, Light ME, van Staden J (2004) J Ethnopharmacol 94: 219-243.

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.bwnjournal-article-abpv54p853kz
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